GLDH
Synonym(s):L -GLDH;L -Glutamate:NAD[P]+ Oxidoreductase (deaminating);Glutamate Dehydrogenase from bovine liver
- CAS NO.:9029-12-3
- Molecular Weight: 0
- MDL number: MFCD01323386
- EINECS: 232-848-4
- Update Date: 2023-04-23 13:52:06
What is GLDH?
The Uses of GLDH
L-Glutamic Dehydrogenase was used to catalyzes the conversion of isocitrate into a-ketoglutarate and carbon dioxide.
Biochem/physiol Actions
Mammalian forms of this enzyme, including this bovine form, can use either NADP(H) or NAD(H) as coenzymes. L-glutamic dehydrogenase plays a unique role in mammalian metabolism. The reverse reaction catalyzed by this enzyme is the only pathway by which ammonia can become bound to the α-carbon atom of an α-carboxylic acid and thus, is the only source of de novo amino acid synthesis in mammalian species. The bovine enzyme is characterized by three sets of properties: It has a reversible concentration-dependent association, producing higher molecular weight forms.Forms tight enzyme-reduced coenzyme-substrate ternary complexes whose rates of dissociation modulate the steady-state reaction rates.Exhibits a wide variety of effects from the binding of any of a number of nucleotide modifiers.L-glutamic dehydrogenase catalyzes the conversion of glutamate to α-ketoglutarate.
Properties of GLDH
storage temp. | -20°C |
form | solution (viscous) |
color | amber |
EPA Substance Registry System | Dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)) (9029-12-3) |
Safety information for GLDH
Signal word | Danger |
Pictogram(s) |
Health Hazard GHS08 |
GHS Hazard Statements |
H334:Sensitisation, respiratory |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P284:Wear respiratory protection. P501:Dispose of contents/container to..… |
Computed Descriptors for GLDH
New Products
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