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HomeProduct name listGeniposide

Geniposide

Synonym(s):(1S,4αS,7αS)- 1-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)- cyclopenta[c]pyran-4-carboxylic acid methyl ester

Geniposide Structural

What is Geniposide?

Chemical properties

White powder

The Uses of Geniposide

Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis. Geniposide is one of the biologically active ingredients of gardenia fruit. Geniposide is widely used in multi-component injection in the treatment of cerebrovascula

What are the applications of Application

Geniposide is an iridoid glycoside

Definition

ChEBI: Geniposide is a terpene glycoside.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation and upregulate downstream antioxidant protein HO-1 expression through the PI3K/Akt signaling pathway, which may account for its neuroprotective and antioxidative activity. Glucagon-like peptide 1 (GLP-1) receptor may also play a critical role in geniposide induced HO-1 expression.

Properties of Geniposide

Melting point: 160.0 to 164.0 °C
Boiling point: 641.4±55.0 °C(Predicted)
Density  1.54±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  H2O: ≥5mg/mL
form  powder
pka 12.80±0.70(Predicted)
color  white to beige
Stability: Hygroscopic
CAS DataBase Reference 24512-63-8(CAS DataBase Reference)

Safety information for Geniposide

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral

Computed Descriptors for Geniposide

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