GENAPOL(R) X-080
Synonym(s):Brij 35;Polidocanol;Polyethylene glycol monoalkyl ether;Polyoxyethylene (9) lauryl ether;Polyoxyethylene lauryl ether, Polyethyleneglycol lauryl ether
- CAS NO.：9043-30-5
- Empirical Formula: HO(CH2CH2O)n(CH2)mH
- Molecular Weight: 0
- MDL number: MFCD00163738
- EINECS: 500-027-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:32
What is GENAPOL(R) X-080?
Characteristics
1. It has a special emulsifying effect on amino silicone oil and dimethyl silicone oil. Compared with the general silicone oil emulsifier, the amount of emulsifier is less, the emulsion is more stable, and it has strong penetrating power, which can penetrate into the fiber.
2. As metal processing aids, multi-functional detergents, decontamination solubilizers, household care cleaning agents, vehicles, public facilities, ultrasonic cleaning agents.
The Uses of GENAPOL(R) X-080
Polyethylene Glycol Monoisotridecyl Ether is a surfactant commonly used in microemulsions for drug delivery.
The Uses of GENAPOL(R) X-080
Genapol X-100 has been used in a study to assess how detergents affect inhibitor potencies against cyclo-oxygenase isoforms. It has also been used in a study to investigate the solubilisation of the membrane-bound D-alanyl-D-alanine carboxypeptidase of Bacillus coagulans.
What are the applications of Application
GENAPOL X-080, 10% Solution, Sterile-Filtered is a detergent used for the isolation of membrane proteins
Definition
ChEBI: Polidocanol is a hydroxypolyether that is nonaethylene glycol in which one of the terminal hydroxy functions is substituted by a lauryl (dodecyl) group. It has a role as a nonionic surfactant, a hepatotoxic agent and a sclerotherapy agent. It is functionally related to a nonaethylene glycol.
What are the applications of Application
Genapol? X-080 was used as the mobile phase component in a high performance liquid chromatography (HPLC) separation study of the selected herbicides using hydro-methanol-micellar liquid chromatography[1]. It was used for the preparation of irritant polymer samples for in vitro cycling studies[2]. In addition, it can be used as an effective solvent for microwave-assisted extraction of flavonoid alkaloids[3].
General Description
Contains 8 ethylene oxides.
References
[1] RADOSLAV HALKO; Milan H. Study of high-performance liquid chromatographic separation of selected herbicides by hydro-methanolic and micellar liquid chromatography using Genapol X-080 non-ionic surfactant as mobile phase constituent[J]. Analytica Chimica Acta, 2002. DOI:10.1016/S0003-2670(02)00590-1.
[2] KELLY P. COLEMAN . Preparation of irritant polymer samples for an in vitro round robin study[J]. Toxicology in Vitro, 2018. DOI:10.1016/j.tiv.2018.01.018.
[3] CHEN SUN; Huizhou L. Application of non-ionic surfactant in the microwave-assisted extraction of alkaloids from Rhizoma Coptidis[J]. Analytica Chimica Acta, 2008. DOI:10.1016/j.aca.2008.02.040.
Properties of GENAPOL(R) X-080
| Melting point: | 41-45 °C(lit.) |
| Boiling point: | 100 °C(lit.) |
| Density | 1.05 g/mL at 25 °C(lit.) |
| vapor pressure | <1 mm Hg ( 20 °C) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | 2-8°C |
| solubility | H2O: 40 mg/mL at 20 °C, clear, colorless |
| form | Jelly Substance at 25°C |
| color | Clear colorless |
| InChI | InChI=1S/C30H62O10/c1-2-3-4-5-6-7-8-9-10-11-13-32-15-17-34-19-21-36-23-25-38-27-29-40-30-28-39-26-24-37-22-20-35-18-16-33-14-12-31/h31H,2-30H2,1H3 |
| CAS DataBase Reference | 9043-30-5(CAS DataBase Reference) |
| EPA Substance Registry System | Polyethylene glycol monoisotridecyl ether (9043-30-5) |
Safety information for GENAPOL(R) X-080
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..… |
Computed Descriptors for GENAPOL(R) X-080
| InChIKey | ONJQDTZCDSESIW-UHFFFAOYSA-N |
| SMILES | C(OCCCCCCCCCCCC)COCCOCCOCCOCCOCCOCCOCCOCCO |
GENAPOL(R) X-080 manufacturer
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