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HomeProduct name listGANGLIOSIDE GD1A DISODIUM SALT

GANGLIOSIDE GD1A DISODIUM SALT

Synonym(s):Disialoganglioside-GD1a (porcine brain, diammonium salt);Ganglioside GD1a, disialo from bovine brain

  • CAS NO.:12707-58-3
  • Empirical Formula: C84H146N4Na2O39
  • Molecular Weight: 1882.04098
  • MDL number: MFCD00130960
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 23:16:16
GANGLIOSIDE GD1A DISODIUM SALT Structural

What is GANGLIOSIDE GD1A DISODIUM SALT?

Description

Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. Ganglioside GD1a mixture contains ganglioside GD1a molecular species with C18:1 and C20:1 sphingoid backbones.

Chemical properties

White powder

The Uses of GANGLIOSIDE GD1A DISODIUM SALT

Ganglioside GD1a Disodium Salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome.

What are the applications of Application

Ganglioside GD1a disodium salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome

General Description

Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose.

Properties of GANGLIOSIDE GD1A DISODIUM SALT

storage temp.  -20°C
solubility  DMSO: soluble
form  lyophilized powder
BRN  6228822

Safety information for GANGLIOSIDE GD1A DISODIUM SALT

Computed Descriptors for GANGLIOSIDE GD1A DISODIUM SALT

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