GANGLIOSIDE GD1A DISODIUM SALT
Synonym(s):Disialoganglioside-GD1a (porcine brain, diammonium salt);Ganglioside GD1a, disialo from bovine brain
- CAS NO.:12707-58-3
- Empirical Formula: C84H146N4Na2O39
- Molecular Weight: 1882.04098
- MDL number: MFCD00130960
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is GANGLIOSIDE GD1A DISODIUM SALT?
Description
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. Ganglioside GD1a mixture contains ganglioside GD1a molecular species with C18:1 and C20:1 sphingoid backbones.
Chemical properties
White powder
The Uses of GANGLIOSIDE GD1A DISODIUM SALT
Ganglioside GD1a Disodium Salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome.
What are the applications of Application
Ganglioside GD1a disodium salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome
General Description
Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose.
Properties of GANGLIOSIDE GD1A DISODIUM SALT
storage temp. | -20°C |
solubility | DMSO: soluble |
form | lyophilized powder |
BRN | 6228822 |
Safety information for GANGLIOSIDE GD1A DISODIUM SALT
Computed Descriptors for GANGLIOSIDE GD1A DISODIUM SALT
New Products
(R)-(-)-2-Amino-1-propanol Tetrahydro-4H-pyran-4-one Bromine 99.5% AR (4 x 500ml) Linseed Oil Extrapure Hydrogen Sulphide Solution Oxalic Acid 0.05 mol/L (0.01N) Solution EDTA 0.1 mol/L (0.2N) for 1000 ml Ferroin 0.025M Solution AR 1,2,3,4-Tetrahydrocarbazol-4-one 4-Hydroxy Carbazole Amino Salicylic Acid. U.S.P. 2 – Methoxy – 5- Sulfamoyl Benzoic acid Acetone Isobutryl oxime ester Sodium Amino Salicylate Dihydrate (PAS Sodium) IP/BP/USP/EP Aloe vera extract 200x Withania somnifera (Ashwagandha Extract) Citrus bioflavonoids Extract Spirulina (Arthrospira platensis) Powder Trikatu Extract Thymol Oil Ethyl 3-(Pyridin-2-Ylamino)Propanoate Bilastine -IP/BP/ Cypermethric Acid Chloride 5-NitrosalicylaldehydeRelated products of tetrahydrofuran
You may like
-
Ganglioside GD1a CAS 12707-58-3View Details
12707-58-3 -
Disialoganglioside GD1a from bovine brain CAS 12707-58-3View Details
12707-58-3 -
7726-95-6 Bromine 99.5% AR (4 x 500ml) 99%View Details
7726-95-6 -
Formamide 99%View Details
75-12-7 -
85-81-4 6-Methoxy-8-Nitroquinoline 99%View Details
85-81-4 -
3-Bromo-4,5-Dihydro-1H-Benzo[B]Azepin-2(3H)-One 99%View Details
86499-96-9 -
29943-42-8 Tetrahydro-4H-pyran-4-one 98+View Details
29943-42-8 -
35320-23-1 98+View Details
35320-23-1