FUSARENON X

Synonym(s):3α,7α,15-Trihydroxy-4β-acetoxy-12,13-epoxytrichothec-9-en-8-one;FusX

CAS NO.：23255-69-8
Empirical Formula: C17H22O8
Molecular Weight: 354.36
MDL number: MFCD00078778
EINECS: 621-752-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 09:02:00

What is FUSARENON X?

Description

Fusarenon X is a type B trichothecene mycotoxin typically derived from Fusarium species. It is primarily found in contaminated cereals. Fusarenon X inhibits protein synthesis, which leads to disruption of DNA synthesis. As this occurs in actively proliferating cells, fusarenon X causes immunosuppression, intestinal malabsorption, developmental toxicity, and genotoxicity. Fusarenon X can be metabolized to fusarenon X-glucoside by infected plants.

The Uses of FUSARENON X

A mycotoxin produced by Fusarium, having immunosuppressive and carcinogenic properties.

Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Properties of FUSARENON X

Melting point:	91-92℃
Boiling point:	407.59°C (rough estimate)
Density	1.2646 (rough estimate)
refractive index	1.4430 (estimate)
Flash point:	2 °C
storage temp.	−20°C
solubility	Dichloromethane: Soluble
pka	11.70±0.70(Predicted)
form	neat
CAS DataBase Reference	23255-69-8

Safety information for FUSARENON X

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H300:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.