FUSARENON X
Synonym(s):3α,7α,15-Trihydroxy-4β-acetoxy-12,13-epoxytrichothec-9-en-8-one;FusX
- CAS NO.：23255-69-8
- Empirical Formula: C17H22O8
- Molecular Weight: 354.36
- MDL number: MFCD00078778
- EINECS: 621-752-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:02:00
What is FUSARENON X?
Description
Fusarenon X is a type B trichothecene mycotoxin typically derived from Fusarium species. It is primarily found in contaminated cereals. Fusarenon X inhibits protein synthesis, which leads to disruption of DNA synthesis. As this occurs in actively proliferating cells, fusarenon X causes immunosuppression, intestinal malabsorption, developmental toxicity, and genotoxicity. Fusarenon X can be metabolized to fusarenon X-glucoside by infected plants.
The Uses of FUSARENON X
A mycotoxin produced by Fusarium, having immunosuppressive and carcinogenic properties.
Safety Profile
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Properties of FUSARENON X
| Melting point: | 91-92℃ |
| Boiling point: | 407.59°C (rough estimate) |
| Density | 1.2646 (rough estimate) |
| refractive index | 1.4430 (estimate) |
| Flash point: | 2 °C |
| storage temp. | −20°C |
| solubility | Dichloromethane: Soluble |
| pka | 11.70±0.70(Predicted) |
| form | neat |
| CAS DataBase Reference | 23255-69-8 |
Safety information for FUSARENON X
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H300:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for FUSARENON X
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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