FR 139317
- CAS NO.：142375-60-8
- Empirical Formula: C33H44N6O5
- Molecular Weight: 604.74
- MDL number: MFCD00467722
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is FR 139317?
The Uses of FR 139317
FR 139317 is a novel, potent endothelin ETA receptor antagonist.
Biological Activity
A highly potent and selective ET A endothelin receptor antagonist (K i values are 1 nM and 7.3 μ M at ET A and ET B subtypes respectively). Active in vivo .
Properties of FR 139317
| Boiling point: | 943.9±65.0 °C(Predicted) |
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at +4°C |
| solubility | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO |
| form | Powder |
| pka | 2.68±0.10(Predicted) |
Safety information for FR 139317
Computed Descriptors for FR 139317
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3,4-Dibenzyloxybenzaldehyde 4-Hydrazinobenzoic acid 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 3-NITRO-2-METHYL ANILINE 4-IODO BENZOIC ACID 4-HYDROXY BENZYL ALCOHOL 4-(3-chloropropyl)morpholine phenylhydrazine hydrochloride (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 4-methoxy-3,5-dinitropyridine 2-(Cyanocyclohexyl)acetic acid 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride tert-butyl 4- (ureidomethyl)benzylcarbamateRelated products of tetrahydrofuran
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