Forchlorfenuron

Description

August 3 is National Watermelon Day, and so this week’s molecules have a watermelon flavor.
Lycopene is the source of the red color in several fruits, notably watermelon (Citrullus lanatus?var.?lanatus) and tomato (Solanum lycopersicum). The pigment, also known as ψ,ψ-carotene, is a linear polyolefin that contains eight isoprene units. It has 13 double bonds, all in the?E-configuration.
In 1910, Swiss chemists Richard M. Willst?tter and Heinrich H. Escher isolated lycopene from tomatoes and determined its structure. But not until 1950 did another Swiss chemist, Paul Karrer, and his co-workers synthesize it.
Lycopene is an antioxidant that may have some health benefits, particularly against cancer and cardiovascular diseases. But agencies such as the European Food Safety Authority and the US Food and Drug Administration are not convinced; on the basis of current evidence, they have refused to label lycopene as a beneficial drug.
Forchlorfenuron, formally 1-(2-chloropyridin-4-yl)-3-phenylurea (CPPU), is a growth regulator that increases the size (and therefore the value) of such fruits as apple, cherry, and kiwi. It’s been used on watermelon too; but at least once, the results were unexpected.
In China in 2011, about 20 farmers applied too much CPPU on their watermelon crops too late in the growing season. The weather conditions were ideal, so much so that the watermelons grew too fast and exploded. The watermelon fragments, about 46 hectares worth, were used to feed fish and pigs.

Description

Forchlorfenuron (68157-60-8) reversibly perturbs mammalian septin assembly, organization and function.? Has no effect on actin or tubulin polymerization.1,2 FCF induces effects on mitosis and migration which phenocopy the effects induced by septin depletion using siRNA.1 A useful tool for exploring the physiological role of septin and its complexes.3,4

Chemical properties

White to faint yellow crystalline powder.

Chemical properties

White Solid

The Uses of Forchlorfenuron

Forchlorfenuronis is a diphenylurea-derivative cytokinin. Forchlorfenuronis is used as a plant growth regulator (PGR). Forchlorfenuronis is commonly used in horticulture to stimulate the growth of kiw i fruit and grapes.

What are the applications of Application

Forchlorfenuron is a cytokinin that promotes cell division and cell differentiation

Definition

ChEBI: Forchlorfenuron is a member of the class of phenylureas that is urea substituted by a phenyl group and a 2-chloropyridin-4-yl group at positions 1 and 3 respectively. It is a plant growth regulator widely used in agriculture for improving fruit quality and fruit size. It has a role as a plant growth regulator. It is a member of phenylureas and a monochloropyridine.

Agricultural Uses

Plant growth regulator: Forchlorfenuron is as a plant growth regulator to promote cell division, and to improve the quality and the yield of fruits, especially table grapes, grape raisins, and kiwi fruit. In some parts of California, forchlorfenuron is said to double the size of Thompson seedless grapes and delay crop maturity up to several weeks. widely used in agriculture on fruits to increase their size,

Trade name

CN-11-3183; KT-30®; SKW 20010

Potential Exposure

Phenylurea/substituted urea plant growth regulator widely used in agriculture on fruits to increase their size, to promote cell division, and to improve the quality and the yield of fruits, especially table grapes, grape raisins, and kiwi fruit. In some parts of California, forchlorfenuron is reputed to double the size of Thompson seedless grapes and delay crop maturity up to several weeks.

Shipping

UN2767 Phenyl urea pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

May react with strong oxidizers such as chlorates, peroxides, nitrates, etc. Dust may form explosive mixture with air.

Waste Disposal

Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. If this material cannot be disposed of according to label instruc tions, it may be dissolved or mixed with a combustible sol vent and burned in a chemical incinerator equipped with an afterburner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers.

References

1) Hu et al. (2008), Forchlorfenuron alters mammalian septin assembly, organization, and dynamics; J. Biol. Chem., 283 29563 2) DeMay et al. (2010), Cellular requirements for the small molecule forchlorfenuron to stabilize the septin cytoskeleton; Cytoskeleton, 67 383 3) Wasik et al. (2012), Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking; Mol. Biol. Cell, 23 3370 4) Vardi-Oknin et al. (2013), Forchlorfenuron disrupts SEPT9_i1 filaments and inhibits HIF-1; PLoS One, 8(8) e73179