FOLIC ACID DIHYDRATE
- CAS NO.:75708-92-8
- Empirical Formula: C19H23N7O8
- Molecular Weight: 477.43
- MDL number: MFCD00150769
- EINECS: 200-419-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is FOLIC ACID DIHYDRATE?
Chemical properties
Yellow to yellow-orange crystalline powd
The Uses of FOLIC ACID DIHYDRATE
Vitamin B9. A B-complex vitamin necessary for the body to produce red blood cellsFolic acid dehydrate is used to form non-covalent complexes with polyethylenimine. It is used for the delivery of genes, which finds application in gene therapy. It is a B-complex vitamin, which is necessary for the body to produce red blood cells.
What are the applications of Application
Folic acid dihydrate is a B-complex vitamin necessary for the body to produce red blood cells
Purification Methods
If paper chromatography indicates impurities, then recrystallise it from hot H2O or from dilute acid [Walker et al. J Am Chem Soc 70 19 1948]. Impurities may be removed by repeated extraction with n-BuOH of a neutral aqueous solution of folic acid (by suspending in H2O and adding N NaOH dropwise till the solid dissolves, then adjusting the pH to ~7.0-7.5) followed by precipitation with acid, filtration, or better collected by centrifugation and recrystallised form hot H2O. [Blakley Biochem J 65 331 1975, Kalifa et al. Helv Chim Acta 6 1 2739 1978.] Chromatography on cellulose followed by filtration through charcoal has also been used to obtain pure acid. [Sakami & Knowles Science 129 274 1959.] UV: max 247 and 296nm ( 12,800 and 18,700) in H2O pH 1.0; 282 and 346nm ( 27.600 and 7,200) in H2O pH 7.0; 256, 284 and 366nm ( 24600, 24,500 and 86,00) in H2O pH 13 [Rabinowitz in The Enzymes (Boyer et al. Eds), 2 185 1960]. [Beilstein 26 III/IV 3944.]
Properties of FOLIC ACID DIHYDRATE
Melting point: | 250°C |
storage temp. | Store at RT. |
solubility | Aqueous Acid (Slightly), Aqueous Base (Slightly), DMSO (Slightly) |
form | Solid |
pka | pK1:8.26 (25°C) |
color | Yellow to Dark Yellow |
Water Solubility | Miscible with water. |
Merck | 14,4221 |
BRN | 100781 |
CAS DataBase Reference | 75708-92-8 |
Safety information for FOLIC ACID DIHYDRATE
Computed Descriptors for FOLIC ACID DIHYDRATE
New Products
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