Fmoc-L-glutamic acid 5-tert-butyl ester
Synonym(s):Fmoc-L -glutamic acid 5-tert-butyl ester;Fmoc-Glu(OtBu)-OH;N-α-Fmoc-L-glutamic acid γ-t.-butyl ester
- CAS NO.：71989-18-9
- Empirical Formula: C24H27NO6
- Molecular Weight: 425.47
- MDL number: MFCD00037135
- EINECS: 276-253-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is Fmoc-L-glutamic acid 5-tert-butyl ester?
Description
Fmoc-L-glutamic acid 5-tert-butyl ester is a Fmoc derivative with an N-substituted tert-butyl ester molecule. It is white or gray-white solid crystals at room temperature and pressure, poor solubility in water and insoluble in petroleum ether, but soluble in ethyl acetate, acetic acid and N,N-dimethylformamide.
Chemical properties
White powder
The Uses of Fmoc-L-glutamic acid 5-tert-butyl ester
Fmoc-Glu(OtBu)-OH (Fmoc-L-glutamic acid 5-tert-butyl ester) can be employed as a:
- Ligand in the synthesis of cis-substituted cyclopropane carboxylic acids via C-H activation of cyclopropane carboxamides using Pd catalyst.
- Linker in the preparation of multi-small molecule-conjugated PTX (paclitaxel) derivatives.
It can be also used as a building block in the preparation of stapled α-helical peptides , and peptide C-terminal thioesters .
General Description
The product number for this product was previously 04-12-1020.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Properties of Fmoc-L-glutamic acid 5-tert-butyl ester
| Melting point: | 83-90 °C |
| Boiling point: | 633.5±55.0 °C(Predicted) |
| alpha | -4.5 º (c=1, 80% acetic acid) |
| Density | 1.232±0.06 g/cm3(Predicted) |
| refractive index | -4 ° (C=1, 80% AcOH) |
| storage temp. | Store below +30°C. |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 3.70±0.10(Predicted) |
| color | White to Almost white |
| optical activity | [α]20/D 5.0±2.0°, c = 1% in acetic acid: water (4:1) |
| BRN | 3636375 |
| CAS DataBase Reference | 71989-18-9(CAS DataBase Reference) |
Safety information for Fmoc-L-glutamic acid 5-tert-butyl ester
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H311:Acute toxicity,dermal H331:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P330:Rinse mouth. P361:Remove/Take off immediately all contaminated clothing. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for Fmoc-L-glutamic acid 5-tert-butyl ester
| InChIKey | OTKXCALUHMPIGM-FQEVSTJZSA-N |
| SMILES | C(O)(=O)[C@H](CCC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
Abamectin manufacturer
JSK Chemicals
1Y
Phone:+919879767970
Whatsapp: +91 9879767970
product: 71989-18-9 N-Fmoc-L-glutamic acid 5-tert-butyl 99%
New Products
Bromine 99.5% AR (4 x 500ml) Fehling's Solution No. B Amino Acid Kit of 23 items set Ammonium Molybdate Reagent Solution Beam's Reagent Solution Ehrlich's Reagent For detection of urobillinogen 4-((2-isopropoxyethoxy)methyl)phenol 4-Hydroxy Carbazole Amino Salicylic Acid. U.S.P. 2 – Methoxy – 5- Sulfamoyl Benzoic acid 1,2,3,4-Tetrahydrocarbazol-4-one Acetone Isobutryl oxime ester Curcuma aromatica Oil Curry leaf Extract Terminalia bellirica Extract Aloe vera extract 200x Withania somnifera (Ashwagandha Extract) Citrus bioflavonoids Extract Ethyl 3-(Pyridin-2-Ylamino)Propanoate Bilastine -IP/BP/ Cypermethric Acid Chloride Methyl Di Chloride (Mdc) 5-Nitrosalicylaldehyde 5-(Difluoromethoxy)-2-Mercapto-1H-Benzimidazole- IP/BP/Related products of tetrahydrofuran
You may like
-
Fmoc-L-Glu-(Otbu)-OH, 98% CAS 71989-18-9View Details
71989-18-9 -
N-Fmoc-L-glutamic acid 5-tert-butyl ester CAS 71989-18-9View Details
71989-18-9 -
5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate CAS 71989-18-9View Details
71989-18-9 -
FMOC-L-Glutamic Acid 5-Tert-Butyl Ester (FMOC-Glu(OtBu)-OH) extrapure CAS 71989-18-9View Details
71989-18-9 -
Fmoc-Glu(OtBu)-OH CAS 71989-18-9View Details
71989-18-9 -
Fmoc-Glu(OtBu)-OH CAS 71989-18-9View Details
71989-18-9 -
71989-18-9 N-Fmoc-L-glutamic acid 5-tert-butyl 99%View Details
71989-18-9 -
7726-95-6 Bromine 99.5% AR (4 x 500ml) 99%View Details
7726-95-6
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.