FMOC-7-AMINO-HEPTANOIC ACID
- CAS NO.：127582-76-7
- Empirical Formula: C22H25NO4
- Molecular Weight: 367.44
- MDL number: MFCD01861353
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is FMOC-7-AMINO-HEPTANOIC ACID?
Description
Fmoc-7-amino-heptanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical properties
White powder
The Uses of FMOC-7-AMINO-HEPTANOIC ACID
7-(Fmoc-amino)heptanoic acid is used as pharmaceutical intermediates.
What are the applications of Application
Fmoc-7-aminoheptanoic acid is a protected aliphatic carboxylic acid
Properties of FMOC-7-AMINO-HEPTANOIC ACID
| Boiling point: | 590.0±33.0 °C(Predicted) |
| Density | 1.191±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| form | Powder |
| pka | 4.77±0.10(Predicted) |
| color | White |
| Water Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 127582-76-7(CAS DataBase Reference) |
Safety information for FMOC-7-AMINO-HEPTANOIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for FMOC-7-AMINO-HEPTANOIC ACID
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