FMOC-5-AMINOPENTANOIC ACID
Synonym(s):5-(Fmoc-amino)pentanoic acid;5-(Fmoc-amino)valeric acid
- CAS NO.：123622-48-0
- Empirical Formula: C20H21NO4
- Molecular Weight: 339.39
- MDL number: MFCD00235889
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is FMOC-5-AMINOPENTANOIC ACID?
Description
Fmoc-5-aminopentanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical properties
White powder
The Uses of FMOC-5-AMINOPENTANOIC ACID
Fmoc-5-aminopentanoic acid, tech grade
The Uses of FMOC-5-AMINOPENTANOIC ACID
5-(Fmoc-amino)valeric acid is used as pharmaceutical intermediate.
Properties of FMOC-5-AMINOPENTANOIC ACID
| Melting point: | 135-136 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3)) |
| Boiling point: | 575.8±33.0 °C(Predicted) |
| Density | 1.232±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Powder |
| pka | 4.71±0.10(Predicted) |
| color | White |
| BRN | 3565625 |
| CAS DataBase Reference | 123622-48-0 |
Safety information for FMOC-5-AMINOPENTANOIC ACID
Computed Descriptors for FMOC-5-AMINOPENTANOIC ACID
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