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HomeProduct name listFMOC-2-NAL-OH

FMOC-2-NAL-OH

Synonym(s):Fmoc-3-(2-naphthyl)-L-alanine

FMOC-2-NAL-OH Structural

What is FMOC-2-NAL-OH?

Description

(S)-N-Fmoc-3-(2-naphthyl) alanine is an Fmoc protected form of alanine. Fmoc protected amino acid is quite useful in the solid phase peptide synthesis. Fmoc can be easily removed with piperidine solution without disturbing the acid labile linker between the peptide and the resin. The Fmoc amino acid is also suitable to be analyzed by HPLC due to its high fluorescent activity. Studies have also shown that (S)-N-Fmoc-3-(2-naphthyl) alanine and related peptides have certain inhibitory effect on Staphylococcus virulence.

Chemical properties

white to slightly yellow powder

The Uses of FMOC-2-NAL-OH

N-Fmoc-3-(2-naphthyl)-L-alanine is used as organic chemical synthesis intermediate.

References

https://www.alfa.com/en/fmoc-protected-compounds/?page=2
http://a2.rqiao.net/patents/US20030050248

Properties of FMOC-2-NAL-OH

Melting point: 155 °C
Boiling point: 549.64°C (rough estimate)
Density  1.2227 (rough estimate)
refractive index  1.6290 (estimate)
storage temp.  2-8°C
solubility  DMF (Sparingly), DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 3.77±0.30(Predicted)
color  White to Off-White
Water Solubility  Slightly soluble in water.
CAS DataBase Reference 112883-43-9(CAS DataBase Reference)

Safety information for FMOC-2-NAL-OH

Computed Descriptors for FMOC-2-NAL-OH

InChIKey JYUTZJVERLGMQZ-SANMLTNESA-N

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