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HomeProduct name listFlunoxaprofen

Flunoxaprofen

Flunoxaprofen Structural

What is Flunoxaprofen?

Description

Flunoxaprofen is an antiinflammatory related to now withdrawn benoxaprofen, reportedly useful in the treatment of rheumatoid arthritis, myositis, synovitis and osteoarthritis. Its major mechanism of action is reported to be lipoxygenase inhibition, thus enabling the control of inflammation with less severe gastric disturbances.

Originator

Ravizza (Italy)

Definition

ChEBI: A monocarboxylic acid that is propionic acid substituted at position 2 by a 2-(4-chlorophenyl)-1,3-benzoxazol-5-yl group (the S-enantiomer). Although it was shown to be effective in treatment of rheumatoid arthritis and osteoarthritis, the clinical use of flunoxaprofen was discontinued due to possible hepatotoxic side-effects.

brand name

Priaxim

Properties of Flunoxaprofen

Melting point: 162-164°
alpha  D20 +50° (c = 2% in DMF)
Boiling point: 419.4±30.0 °C(Predicted)
Density  1.334±0.06 g/cm3(Predicted)
pka 4.36±0.30(Predicted)

Safety information for Flunoxaprofen

Computed Descriptors for Flunoxaprofen

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