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HomeProduct name listFGF-401

FGF-401

  • CAS NO.:1708971-55-4
  • Empirical Formula: C25H30N8O4
  • Molecular Weight: 506.56
  • MDL number: MFCD31381923
  • Update Date: 2024-11-19 23:02:33
FGF-401 Structural

What is FGF-401?

Description

FGF401 is an inhibitor of FGF receptor 4 (FGFR4; IC50 = 1.9 nM). It inhibits proliferation of Huh7 carcinoma cells with an IC50 value of 12 nM. FGF401 induces bile acid synthesis in dogs, increasing plasma and fecal levels of bile acids when administered at a dose of 45 mg/kg per day for four weeks. It also decreases serum cholesterol when administered at doses ranging from 5 to 45 mg/kg per day.

Properties of FGF-401

Boiling point: 852.1±65.0 °C(Predicted)
Density  1.39±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  DMSO:5.4(Max Conc. mg/mL);10.66(Max Conc. mM)
Chloroform:30.0(Max Conc. mg/mL);59.22(Max Conc. mM)
form  A crystalline solid
pka 11.40±0.20(Predicted)
color  White to off-white

Safety information for FGF-401

Computed Descriptors for FGF-401

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