Ferritin
- CAS NO.:79468-83-0
- Molecular Weight: 0
What is Ferritin?
Description
Ferritin is the cellular storage protein for iron. Most of the iron stored in the body is bound to ferritin. Ferritin is found in the liver, spleen, skeletal muscles, and bone marrow. A small amount of ferritin is found in blood. Ferritins are also able to store a significant quantity of iron within a hollow core, and act as storage systems for iron within cells. The primary role of ferritin is to protect cells from the damage caused by the Fenton reaction: free Fe(II) in oxidizing conditions produces harmful reactive oxygen species that can damage the cellular machinery.
The serum ferritin concentration normally correlates well with total-body iron stores, making its measurement important in the diagnosis of disorders of iron metabolism. Ferritin level blood test can be used to test ferritin levels. Low ferritin levels could be caused by iron deficiency, anemia, excessive menstrual bleeding, stomach conditions that affect intestinal absorption, and internal bleeding. High ferritin levels indicate certain conditions including hemochromatosis, rheumatoid arthritis, liver disease, hyperthyroidism, adult Still’s disease, type 2 diabetes, leukemia, Hodgkin’s lymphoma, iron poisoning, and frequent blood transfusions.
Definition
An iron–protein complex in which iron is stored in the intestinal mucosa, spleen, and liver. It regulates iron transport from the intestinal lumen to plasma in circulating blood.
Hazard
Questionable carcinogen; neoplastigen; mutagen.
References
[1] http://www.webmd.com
[2] http://www.healthline.com
Properties of Ferritin
storage temp. | 2-8°C |
CAS DataBase Reference | 79468-83-0 |
Safety information for Ferritin
Computed Descriptors for Ferritin
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
You may like
-
Dabigatran Acyl-O2-D-Glucuronide Trifluoroacetic Acid SaltView Details
-
Dechloro DesloratadineView Details
-
Dehydro DesloratadineView Details
-
Edoxaban Impurity 57View Details
2089454-69-1 -
Eltrombopag N-Oxide ImpurityView Details
2734533-17-4 -
Empagliflozin Bromo ImpurityView Details
-
Glycopyrronium Bromide EP Impurity IView Details
1404617-94-2 -
Ipratropium EP Impurity BView Details
58073-59-9