Creatine Phosphokinase
Synonym(s):Creatine Kinase;Creatine Phosphokinase, Rabbit Skeletal Muscle;Phosphocreatine phosphokinase;rCPK;ATP: Creatine N-Phosphotransferase
- CAS NO.:9001-15-4
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00130876
- EINECS: 232-585-5
- Update Date: 2024-12-18 13:37:16
What is Creatine Phosphokinase?
The Uses of Creatine Phosphokinase
The enzyme from Sigma has been used in the measurement of phosphocreatine in hippocampal neurons isolated from rat brains.
The Uses of Creatine Phosphokinase
The product has been used for tATPase assay of myofibrillar protein isolated from rabbit. This assay evaluated the kinetic influence of bound creatine kinase (CK) on Ca2+-activated myosin ATPase. The product has also been used for the enzymatic hydrolysis of protein samples during tryptophan estimation by pyrolysis gas chromatography.
Biochem/physiol Actions
Creatine kinase plays a key role in the energy metabolism of cells with intermittently high and fluctuating energy requirements. Examples of such cells include cardiac or skeletal muscle cells and neural tissues of brain and retina. The enzyme catalyzes the reversible transfer of the phosphoryl group from phosphorylcreatine to ADP, in order to generate ATP. The molecular mass of the protein is found to be approximately 80,000 Da. It is made up of 2 subunits, each having a molecular weight of 40,000 ± 2000. The lighter subunit is present in larger amounts.
Properties of Creatine Phosphokinase
storage temp. | -20°C |
solubility | 0.25 M glycyl-glycine, pH 7.4: soluble5.0mg/mL, clear, colorless to slightly yellow |
form | salt-free, lyophilized powder |
color | white |
CAS DataBase Reference | 9001-15-4 |
EPA Substance Registry System | Kinase (phosphorylating), creatine (9001-15-4) |
Safety information for Creatine Phosphokinase
Computed Descriptors for Creatine Phosphokinase
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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