FENOBAM
Synonym(s):N-(3-Chlorophenyl)-N′-(4,5-dihydro-1-methyl-4-oxo-1H-imidazole-2-yl)urea
- CAS NO.：57653-26-6
- Empirical Formula: C11H11ClN4O2
- Molecular Weight: 266.68
- MDL number: MFCD00868019
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is FENOBAM?
Description
During the 1970s and 1980s, researchers at McNeil Laboratories synthesized fenobam from creatine and developed it as an anxiolytic drug. Its molecular target was unknown at the time, but in 2005 fenobam was discovered to be a potent, selective mGluR5?antagonist. This finding prompted structure–activity relationship studies with fenobam as the lead compound. Among other potential uses, it may lead to a treatment for autism.
The Uses of FENOBAM
Fenobam is a potent and selective non-competitive mGluR5 antagonist.
The Uses of FENOBAM
Sedative-hypnotic.
What are the applications of Application
Fenobam is a potent and selective non-competitive mGluR5 antagonist
storage
Room temperature
Properties of FENOBAM
| Density | 1.47±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | DMSO: >20mg/mL |
| pka | 8.32±0.20(Predicted) |
| form | solid |
| color | white |
Safety information for FENOBAM
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H300:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P233:Keep container tightly closed. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304:IF INHALED: P312:Call a POISON CENTER or doctor/physician if you feel unwell. P321:Specific treatment (see … on this label). P330:Rinse mouth. P340:Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362:Take off contaminated clothing and wash before reuse. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P403:Store in a well-ventilated place. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for FENOBAM
Abamectin manufacturer
ALS INDIA LIFE SCIENCES
1Y
Phone:+91-8977036379
Whatsapp: +91 8008166674
product: 57653-26-6 Fenobam 98%
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