Ethyltriphenylphosphonium bromide
Synonym(s):TEP
- CAS NO.:1530-32-1
- Empirical Formula: C20H20BrP
- Molecular Weight: 371.25
- MDL number: MFCD00011838
- EINECS: 216-223-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-24 19:19:26
What is Ethyltriphenylphosphonium bromide?
Chemical properties
White to off-white crystalline powder
The Uses of Ethyltriphenylphosphonium bromide
Ethyltriphenylphosphonium Bromide (ETPB) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.
- Ethyltriphenylphosphonium bromide acts as a reactant in the synthesis of D-amino acids from L-cysteine-derived thiazolidines, Leiodolide A through aldol reactions and Horner-Wadsworth-Emmons olefination.
- It is also used in the preparation of cycloalkanoindolines through diastereoselective intramolecular inimo-ene reactions.
- it is used as a reagent in solid-state metathesis polycondensation to prepare alkyl-dipropenylthiophene monomers.
- Mizoroki-Heck cyclization and cascading Tsuji-Trost cyclization reactions.
Description
Ethyltriphenyl phosphonium bromide (ETPB) is a white to off-white crystalline powder used as a phase-transfer catalyst in the production of epoxy resins and powder coatings, and as a pharmaceutical intermediate.
Purification Methods
Recrystallise it from H2O and dry it in high vacuum at 100o. IR has bands at 1449, 1431 and 997cm-1 . [Wittig & Wittenberg Justus Liebigs Ann Chem 606 1 1957, Bergmann & Dusza J Org Chem 23 1245 1958, Beilstein 16 IV 982.]
Properties of Ethyltriphenylphosphonium bromide
Melting point: | 203-205 °C(lit.) |
Boiling point: | 240℃[at 101 325 Pa] |
Density | 1.38[at 20℃] |
vapor pressure | 0-0.1Pa at 20-25℃ |
Flash point: | 200 °C |
storage temp. | Inert atmosphere,Room Temperature |
solubility | 174g/l soluble |
form | Crystalline Powder |
color | White to off-white |
Water Solubility | 120 g/L (23 ºC) |
Sensitive | Hygroscopic |
BRN | 3599630 |
CAS DataBase Reference | 1530-32-1(CAS DataBase Reference) |
EPA Substance Registry System | Phosphonium, ethyltriphenyl-, bromide (1530-32-1) |
Safety information for Ethyltriphenylphosphonium bromide
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral H318:Serious eye damage/eye irritation H412:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Ethyltriphenylphosphonium bromide
InChIKey | JHYNXXDQQHTCHJ-UHFFFAOYSA-M |
Abamectin manufacturer
Cardkem Pharma Pvt Ltd
ACME SUJAN CHEMICALS
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SNECOFRi PVT LTD
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Dishman Carbogen Amcis Ltd (Dishman Group)
Delta Finochem Pvt Ltd
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