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HomeProduct name listEthyl (R)-(+)-4-chloro-3-hydroxybutyrate

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate

  • CAS NO.:90866-33-4
  • Empirical Formula: C6H11ClO3
  • Molecular Weight: 166.6
  • MDL number: MFCD00211242
  • EINECS: 626-176-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate Structural

What is Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate?

Chemical properties

Colorless to light yellow liqui

The Uses of Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate is a chiral building block that can be used:

  • To prepare allyl stannane, a precursor for the total synthesis of macrolide iriomoteolide-1b.
  • As a starting material for the synthesis of a chiral g-αmino acid fragment, which in turn is used to prepare the immunosuppressive agent FR252921.

Properties of Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate

Melting point: 93-95 °C
Boiling point: 93-95 °C/5 mmHg (lit.)
alpha  14 º (neat)
Density  1.19 g/mL at 25 °C (lit.)
refractive index  n20/D 1.452
Flash point: >110°C
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly)
form  Oil
pka 13.23±0.20(Predicted)
Specific Gravity 1.190
color  Clear Colourless
optical activity [α]23/D +14°, neat
CAS DataBase Reference 90866-33-4(CAS DataBase Reference)

Safety information for Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H318:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate

InChIKey ZAJNMXDBJKCCAT-RXMQYKEDSA-N

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