Ethyl 5-nitroindole-2-carboxylate
- CAS NO.：16732-57-3
- Empirical Formula: C11H10N2O4
- Molecular Weight: 234.21
- MDL number: MFCD00216477
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:19
What is Ethyl 5-nitroindole-2-carboxylate?
Chemical properties
yellow to brown powder
The Uses of Ethyl 5-nitroindole-2-carboxylate
Ethyl 5-Nitroindole-2-carboxylate is used as a reagent in the synthesis of indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. Ethyl 5-Nitroindole-2-carboxylate is also a useful synthetic intermediate in the synthesis of Delavirdine (D230625) which is a bisheteroarylpiperazine (BHAP) reverse transcriptase inhibitor.
Properties of Ethyl 5-nitroindole-2-carboxylate
| Melting point: | 220-225 °C |
| Boiling point: | 376.52°C (rough estimate) |
| Density | 1.3240 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | Powder |
| pka | 13.26±0.30(Predicted) |
| color | Yellow to brown |
| Water Solubility | negligible |
| CAS DataBase Reference | 16732-57-3(CAS DataBase Reference) |
Safety information for Ethyl 5-nitroindole-2-carboxylate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Ethyl 5-nitroindole-2-carboxylate
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 4-Hydrazinobenzoic acid 3,4-Dibenzyloxybenzaldehyde Electrolytic Iron Powder 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 4-HYDROXY BENZYL ALCOHOL 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) S-2-CHLORO PROPIONIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 3-(Hydroxymethyl)benzoate N-Boc-2-chloroethylamine 1-Bromo-2-methoxy-3-nitrobenzene N-Methyl-3-cyclopenten-1-amine 2-Bromo-3-hydroxybenzaldehyde 1H-indazole-5-carboxamideRelated products of tetrahydrofuran
You may like
-
Ethyl 5-Nitroindole-2-carboxylate CAS 16732-57-3View Details
16732-57-3 -
Ethyl 5-nitroindole-2-carboxylate 98% CAS 16732-57-3View Details
16732-57-3 -
Ethyl 5-nitroindole-2-carboxylate 98% (HPLC) CAS 16732-57-3View Details
16732-57-3 -
7441-43-2 98%View Details
7441-43-2 -
1260741-78-3 6-Bromo-3-iodo-1-methyl-1H-indazole 98%View Details
1260741-78-3 -
4-bromo-3,5-dimethylbenzenesulfonyl chloride 1581266-79-6 98%View Details
1581266-79-6 -
2490430-37-8 98%View Details
2490430-37-8 -
N-(5-Amino-2-methylphenyl)acetamide 5434-30-0 98%View Details
5434-30-0
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.