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HomeProduct name listETHYL 5-METHYLINDOLE-2-CARBOXYLATE

ETHYL 5-METHYLINDOLE-2-CARBOXYLATE

Synonym(s):5-Methylindole-2-carboxylic acid ethyl ester;NSC 30928

ETHYL 5-METHYLINDOLE-2-CARBOXYLATE Structural

What is ETHYL 5-METHYLINDOLE-2-CARBOXYLATE?

The Uses of ETHYL 5-METHYLINDOLE-2-CARBOXYLATE

Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions 1 Reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists 2 Reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents 3 Reactant for Friedel-Crafts acylation with nitrobenzoyl chloride 4 Reactant for oximation reactions 5

The Uses of ETHYL 5-METHYLINDOLE-2-CARBOXYLATE

Reactant for synthesis of oxazino[4,3-a]indoles via cascade addition-cyclization reactions, reactant for preparation of indolecarboxamides as cannabinoid CB1 receptor antagonists, reactant for preparation of indole-3-propionic acids as antiinflammatory and analgesic agents, reactant for Friedel-Crafts acylation with nitrobenzoyl chloride. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine. ? Reactant for oximation reactions

What are the applications of Application

Ethyl 5-methylindole-2-carboxylate is a compound for the synthesis of biological active chemicals

General Description

Ethyl 5-methylindole-2-carboxylate (5-Methylindole-2-carboxylic acid ethyl ester) is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.

Properties of ETHYL 5-METHYLINDOLE-2-CARBOXYLATE

Melting point: 162-164°C
Boiling point: 236°C 4mm
Density  1.177±0.06 g/cm3(Predicted)
Flash point: 236°C/4mm
storage temp.  Sealed in dry,Room Temperature
pka 15.19±0.30(Predicted)
color  Light yellow to beige
Water Solubility  Soluble in methanol, and dichloromethane. Insoluble in water.
BRN  159437
CAS DataBase Reference 16382-15-3(CAS DataBase Reference)

Safety information for ETHYL 5-METHYLINDOLE-2-CARBOXYLATE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305:IF IN EYES:
P351:Rinse cautiously with water for several minutes.

Computed Descriptors for ETHYL 5-METHYLINDOLE-2-CARBOXYLATE

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