Ethyl 4,4,4-trifluorocrotonate

Synonym(s):Ethyl 4,4,4-trifluoro-2-butenoate

CAS NO.：25597-16-4
Empirical Formula: C6H7F3O2
Molecular Weight: 168.11
MDL number: MFCD00009903
EINECS: 607-752-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:43:18

Ethyl 4,4,4-trifluorocrotonate Structural

What is Ethyl 4,4,4-trifluorocrotonate?

Chemical properties

clear colorless liquid

The Uses of Ethyl 4,4,4-trifluorocrotonate

Ethyl trans-4,4,4-Trifluorocrotonate, is an intermediate used in the synthesis of various pharmaceutically active molecules and agricultural products. It can also be used in the synthesis of novel amino trifluoromethyl cyclopropane carboxylic acid derivatives in the presence of nucleophilic reagents.

What are the applications of Application

Ethyl 4,4,4-trifluorocrotonate is can undergo diasteroselective Michael addition reaction with ethyl crotonate

Properties of Ethyl 4,4,4-trifluorocrotonate

Boiling point:	114-115 °C(lit.)
Density	1.125 g/mL at 25 °C(lit.)
refractive index	n20/D 1.3601(lit.)
Flash point:	78 °F
storage temp.	Inert atmosphere,Room Temperature
form	Liquid
color	Clear colorless
Specific Gravity	1.125
BRN	1707262
CAS DataBase Reference	25597-16-4(CAS DataBase Reference)
NIST Chemistry Reference	Ethyl 4,4,4-trifluorocrotonate(25597-16-4)

Safety information for Ethyl 4,4,4-trifluorocrotonate

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.