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HomeProduct name listEthyl (3S)-piperidine-3-carboxylate

Ethyl (3S)-piperidine-3-carboxylate

Synonym(s):(S)-3-Piperidinecarboxylic acid ethyl ester;(S)-Ethyl nipecotate

  • CAS NO.:37675-18-6
  • Empirical Formula: C8H15NO2
  • Molecular Weight: 157.21
  • MDL number: MFCD00792499
  • EINECS: 609-464-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-24 21:11:45
Ethyl (3S)-piperidine-3-carboxylate Structural

What is Ethyl (3S)-piperidine-3-carboxylate?

Chemical properties

Colorless liquid

The Uses of Ethyl (3S)-piperidine-3-carboxylate

Reactant for synthesis of:

  • DPP-4 inhibitors
  • JAK2 inhibitors
  • Serotonin and noradrenaline reuptake inhibitors
  • Human tryptase inhibitors
  • Anti-thrombotic nicecotamides

Reactive for oxidative C-arylation of free (NH)-heterocycles via direct (sp3) C-H bond functionalization

Properties of Ethyl (3S)-piperidine-3-carboxylate

Boiling point: 102-104 °C/7 mmHg(lit.)
Density  1.043 g/mL at 25 °C
refractive index  n20/D 1.471
Flash point: 77 °C
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form  clear liquid
pka 9.35±0.10(Predicted)
Specific Gravity 1.012
color  Colorless to Almost colorless
Sensitive  Light, Air & Moisture Sensitive
CAS DataBase Reference 37675-18-6(CAS DataBase Reference)

Safety information for Ethyl (3S)-piperidine-3-carboxylate

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H318:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Ethyl (3S)-piperidine-3-carboxylate

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