Ethyl 2-acetylcaprylate

CAS NO.：29214-60-6
Empirical Formula: C12H22O3
Molecular Weight: 214.3
MDL number: MFCD00026889
EINECS: 249-518-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:35

What is Ethyl 2-acetylcaprylate?

Physical properties

Colorless slightly oily liquid. Very slightly soluble in water, soluble in akohol, miscible with oils.

Occurrence

Has apparently not been reported to occur in nature.

Preparation

By the alkylation of ethyl acetoacetate with hexyl bromide or by any other suitable method. Uses: In public use since the 1950s. Use in fragrances in the USA amounts to approximately 10001b/yr.

Production Methods

Ethyl 2-acetylcaprylate can be produced by condensation of Ethyl acetate and Hexyl acetate, using Sodium ethoxide catalyst.

Synthesis Reference(s)

Journal of the American Chemical Society, 64, p. 580, 1942 DOI: 10.1021/ja01255a035

Properties of Ethyl 2-acetylcaprylate

Boiling point:	149 °C / 25mmHg
Density	0.94
refractive index	1.4320 to 1.4360
FEMA	4459 \| ETHYL 2-ACETYLOCTANOATE
form	clear liquid
pka	11.89±0.59(Predicted)
color	A colourless slightly oily liquid.
Odor	at 100.00 %. methyl dihydrojasmonate fruity jasmin waxy herbal
JECFA Number	1958
CAS DataBase Reference	29214-60-6(CAS DataBase Reference)
EPA Substance Registry System	Octanoic acid, 2-acetyl-, ethyl ester (29214-60-6)

Safety information for Ethyl 2-acetylcaprylate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..…