ETHYL 1-PIPERIDINEACETATE

Synonym(s):Piperidin-1-ylacetic acid ethyl ester

CAS NO.：23853-10-3
Empirical Formula: C9H17NO2
Molecular Weight: 171.24
MDL number: MFCD00134496
SAFETY DATA SHEET (SDS)
Update Date: 2022-12-30 16:20:48

What is ETHYL 1-PIPERIDINEACETATE?

Chemical properties

clear light yellow liquid

The Uses of ETHYL 1-PIPERIDINEACETATE

Reactant for synthesis of:
Nicotinic acid receptor agonists for treatment of dyslipidemia
1-Alkylcyclanols with side chain functions
Benzhydrylamides for pharmacochemical studies

Reactant for:
Elimination reactions
Hydrogenation of esters to alcohols

General Description

Ethyl 1-piperidineacetate (Piperidin-1-ylacetic acid ethyl ester) is an α-amino acid ethyl ester derivative. Thermal decomposition of ethyl 1-piperidineacetate in gas phase has been studied by ab initio theoretical methods. The kinetics of gas-phase decomposition of ethyl 1-piperidineacetate to the corresponding α-amino acid derivative and ethylene over the temperature range of 360-430°C and pressure range of 26-86Torr has been investigated. Alkylation reaction of ethyl 1-piperidineacetate with ethyl bromoacetate in absolute ethanol has been reported to obey second order kinetics.

Properties of ETHYL 1-PIPERIDINEACETATE

Boiling point:	109-111 °C/25 mmHg (lit.)
Density	0.984 g/mL at 25 °C (lit.)
refractive index	n20/D 1.453(lit.)
Flash point:	196 °F
pka	7.44±0.10(Predicted)
Specific Gravity	0.984
BRN	123142
CAS DataBase Reference	23853-10-3(CAS DataBase Reference)

Safety information for ETHYL 1-PIPERIDINEACETATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.