ethiazide
- CAS NO.：1824-58-4
- Empirical Formula: C9H12ClN3O4S2
- Molecular Weight: 325.79
- MDL number: MFCD00867314
- EINECS: 217-358-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is ethiazide?
Originator
Ethiazide,Tokyo Tanabe,Japan,1970
Definition
ChEBI: Ethiazide is a benzothiadiazine.
Manufacturing Process
A mixture of 2.9 grams of 5-chloro-2,4-disulfamyl-aniline in 20 ml of anhydrous diethylene glycoldimethylether, 0.44 gram of propionaldehyde and 0.5 ml of a solution of hydrogen chloride in ethyl acetate (109.5 grams hydrogen chloride per 1,000 ml) is heated to 80° to 90°C and maintained at that temperature for 1 hour. The reaction mixture is concentrated under reduced pressure; on addition of water, the product separates and is then recrystallized from ethanol or aqueous ethanol to yield the desired 6-chloro-3- ethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, MP 269° to 270°C.
Therapeutic Function
Diuretic, Cardiotonic, Smooth muscle relaxant, Respiratory stimulant
Properties of ethiazide
| Melting point: | 269-270° |
| Boiling point: | 563.5±60.0 °C(Predicted) |
| Density | 1.526±0.06 g/cm3(Predicted) |
| pka | 9.01±0.40(Predicted) |
Safety information for ethiazide
Computed Descriptors for ethiazide
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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