ethiazide
- CAS NO.:1824-58-4
- Empirical Formula: C9H12ClN3O4S2
- Molecular Weight: 325.79
- MDL number: MFCD00867314
- EINECS: 217-358-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is ethiazide?
Originator
Ethiazide,Tokyo Tanabe,Japan,1970
Definition
ChEBI: Ethiazide is a benzothiadiazine.
Manufacturing Process
A mixture of 2.9 grams of 5-chloro-2,4-disulfamyl-aniline in 20 ml of anhydrous diethylene glycoldimethylether, 0.44 gram of propionaldehyde and 0.5 ml of a solution of hydrogen chloride in ethyl acetate (109.5 grams hydrogen chloride per 1,000 ml) is heated to 80° to 90°C and maintained at that temperature for 1 hour. The reaction mixture is concentrated under reduced pressure; on addition of water, the product separates and is then recrystallized from ethanol or aqueous ethanol to yield the desired 6-chloro-3- ethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, MP 269° to 270°C.
Therapeutic Function
Diuretic, Cardiotonic, Smooth muscle relaxant, Respiratory stimulant
Properties of ethiazide
Melting point: | 269-270° |
Boiling point: | 563.5±60.0 °C(Predicted) |
Density | 1.526±0.06 g/cm3(Predicted) |
pka | 9.01±0.40(Predicted) |
Safety information for ethiazide
Computed Descriptors for ethiazide
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-(2,4-Dimethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione 6-Bromo-3-iodo-1-methyl-1H-indazole N-octanoyl benzotriazole 3,4-Dibenzyloxybenzaldehyde 4-Hydrazinobenzoic acid Electrolytic Iron Powder 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 4-HYDROXY BENZYL ALCOHOL 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) S-2-CHLORO PROPIONIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine N-Boc-L-proline methyl ester 2-(BOC-Amino)4-picoline 1-(4-Methylphenylsulfonyl)-1H-1,2,3-benzotriazole 1-(2-Chlorobenzyl)-4-nitro-1H-pyrazoleRelated products of tetrahydrofuran
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