ERGOCRISTINE

CAS NO.：511-08-0
Empirical Formula: C35H39N5O5
Molecular Weight: 609.73
MDL number: MFCD00215848
EINECS: 208-120-7
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-28 13:53:25

What is ERGOCRISTINE?

The Uses of ERGOCRISTINE

A derivative of lysergic acid and a natural ergot alkaloid which is a member of the ergotoxine group. Its intraocular pressure lowering effect makes it potential candidate for future applications in ocular pharmacology.

Definition

ChEBI: Ergotaman bearing benzyl, hydroxy, and isopropyl groups at the 5', 12' and 2' positions, respectively, and oxo groups at positions 3', 6', and 18. It is a natural ergot alkaloid.

Purification Methods

It crystallises with 2 molecules of solvent of crystallisation from *benzene. [Stadler et al. Helv Chim Acta 52 1549 1969, Beilstein 25 III/IV 966, 27 II 860.]

Properties of ERGOCRISTINE

Melting point:	155-157 °C(lit.)
Boiling point:	655.69°C (rough estimate)
alpha	D20 -183° (chloroform)
Density	1.1839 (rough estimate)
refractive index	1.7500 (estimate)
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	9.59±0.60(Predicted)
color	Off-white
Stability:	Hygroscopic

Safety information for ERGOCRISTINE

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.