Endoxifen
- CAS NO.：112093-28-4
- Empirical Formula: C25H27NO2
- Molecular Weight: 373.49
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Endoxifen?
Chemical properties
Off-White to Pink Solid
The Uses of Endoxifen
A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca
The Uses of Endoxifen
A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.
What are the applications of Application
(Z)-4-Hydroxy-N-desmethyl Tamoxifen (mixture of isomers) is a novel metabolite of tamoxifen
Definition
ChEBI: 4-Hydroxy-N-desmethyltamoxifen is a stilbenoid.
Properties of Endoxifen
| Melting point: | 127-129°C |
| Boiling point: | 519.3±50.0 °C(Predicted) |
| Density | 1.099±0.06 g/cm3(Predicted) |
| storage temp. | Amber Vial, -86°C Freezer, Under Inert Atmosphere |
| solubility | DMSO : 50 mg/mL (133.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | Powder |
| pka | 10.36±0.15(Predicted) |
| color | White to off-white |
| Stability: | Light Sensitive, Temperature Sensitive |
Safety information for Endoxifen
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H361:Reproductive toxicity H372:Specific target organ toxicity, repeated exposure H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
Computed Descriptors for Endoxifen
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