EMD-9806
- CAS NO.:14334-41-9
- Empirical Formula: C21H28ClN
- Molecular Weight: 329.91
- MDL number: MFCD01735211
- EINECS: 238-284-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-21 16:56:50
What is EMD-9806?
Originator
Sistalgin, Bracco, Italy,1974
The Uses of EMD-9806
A cyclohexanamine derivative with spasmolytic and analgesic activity. An effective anticholinergic agent.
Manufacturing Process
20 g 4,4-diphenyl-cyclohexen-(2)-one, 10 g isopropylamine, and 50 ml tetrahydrofuran are agitated for 10 hours in a bomb tube at 200°C. Subsequently, the reaction mixture is cooled, and the tetrahydrofuran and theexcess isopropylamine are distilled off. The remaining Schiff base is dissolved in methanol and after the addition of 2 g platinum oxide, the base is hydrogenated at normal pressure and room temperature until a quantity of hydrogen corresponding to 2 mols has been absorbed.
The mixture is filtered off from the catalyst, made acidic with dilute hydrochloric acid, and the methanol is removed under vacuum. The remaining aqueous solution is made alkaline with solution of sodium hydroxide and extracted with ether. After drying and concentrating the ether extract, there is obtained 17 g 1-isopropylamino-4,4-diphenyl-cyclohexane, boiling point 164°C to 165°C/0.05 mm. The hydrochloride melts at 230°C.
Therapeutic Function
Spasmolytic
Properties of EMD-9806
Melting point: | 230° |
Safety information for EMD-9806
Computed Descriptors for EMD-9806
New Products
2,2-diethoxyethanethioamide Tubulysin F Tubulysin C 2,2-Difluoropropylamine hydrochloride CYCLOBUTYLAMINE HYDROCHLORIDE 4,4-DIFLUOROPIPERIDINE 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 4-(Benzyloxy)-3-bromophenylacetic Acid 1-(1,1-Difluoroethyl)-2-fluorobenzene (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Calcium Sodium Phosphosilicate IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Imeglimin Hydrochloride IH Lubiprostone Magnesium Trisilicate Latanoprostene Bunod Flame Retardant Zinc Borate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate methyl 3-fluoro-4- thiomorpholino phenylcarbamate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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