EMD 386088 HYDROCHLORIDE
- CAS NO.：54635-62-0
- Empirical Formula: C14H15ClN2
- Molecular Weight: 246.74
- MDL number: MFCD09038557
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:39
What is EMD 386088 HYDROCHLORIDE?
What are the applications of Application
EMD 386088 hydrochloride is a potent SR-6 agonist
Definition
ChEBI: 5-chloro-2-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole is a member of indoles.
Biological Activity
Potent 5-HT 6 receptor agonist (EC 50 = 1.0 nM) that displays selectivity over other 5-HT receptors (IC 50 values are 7.4, 110, 180, 240, 450, 620, 660 and 3000 nM for 5-HT 6 , 5-HT 1D , 5-HT 1B , 5-HT 2A , 5-HT 2C , 5-HT 4 , 5-HT 1A and 5-HT 7 receptors respectively). Shows moderate affinity at 5-HT 3 receptors (IC 50 = 34 nM).
Properties of EMD 386088 HYDROCHLORIDE
| Boiling point: | 438.1±45.0 °C(Predicted) |
| Density | 1.242±0.06 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| pka | 16.73±0.30(Predicted) |
Safety information for EMD 386088 HYDROCHLORIDE
Computed Descriptors for EMD 386088 HYDROCHLORIDE
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