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HomeProduct name listELEUTHEROSIDE B1(RG)

ELEUTHEROSIDE B1(RG)

ELEUTHEROSIDE B1(RG) Structural

What is ELEUTHEROSIDE B1(RG)?

Chemical properties

White crystalline powder, soluble in chloroform, derived from the dried rhizome of Acanthopanax senticosus.

Biological Activity

Eleutheroside B1, a coumarin compound, has broad-spectrum anti-human influenza virus (influenza virus) activity with IC50 values of 64-125μg/ml. It mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits mRNA expression of multiple chemokine genes and influenza virus nucleoprotein (NP) gene with low cytotoxicity. Has antiviral and anti-inflammatory activity.

in vitro

Eeutheroside B1 (100 μg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells.

RT-PCR

Cell Line: Virus-infected A549 cells
Concentration: 100 μg/ml
Incubation Time: 24 hours
Result: The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased.

Properties of ELEUTHEROSIDE B1(RG)

Boiling point: 675.0±55.0 °C(Predicted)
Density  1.524±0.06 g/cm3(Predicted)
storage temp.  4°C, away from moisture and light
pka 12.65±0.70(Predicted)
form  Solid
color  White to off-white

Safety information for ELEUTHEROSIDE B1(RG)

Computed Descriptors for ELEUTHEROSIDE B1(RG)

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