ELEUTHEROSIDE B1(RG)
- CAS NO.：16845-16-2
- Empirical Formula: C17H20O10
- Molecular Weight: 384.34
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:09
What is ELEUTHEROSIDE B1(RG)?
Chemical properties
White crystalline powder, soluble in chloroform, derived from the dried rhizome of Acanthopanax senticosus.
Biological Activity
Eleutheroside B1, a coumarin compound, has broad-spectrum anti-human influenza virus (influenza virus) activity with IC50 values of 64-125μg/ml. It mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits mRNA expression of multiple chemokine genes and influenza virus nucleoprotein (NP) gene with low cytotoxicity. Has antiviral and anti-inflammatory activity.
in vitro
Eeutheroside B1 (100 μg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells.
RT-PCR
| Cell Line: | Virus-infected A549 cells |
| Concentration: | 100 μg/ml |
| Incubation Time: | 24 hours |
| Result: | The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased. |
Properties of ELEUTHEROSIDE B1(RG)
| Boiling point: | 675.0±55.0 °C(Predicted) |
| Density | 1.524±0.06 g/cm3(Predicted) |
| storage temp. | 4°C, away from moisture and light |
| pka | 12.65±0.70(Predicted) |
| form | Solid |
| color | White to off-white |
Safety information for ELEUTHEROSIDE B1(RG)
Computed Descriptors for ELEUTHEROSIDE B1(RG)
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