DULCIN

Chemical properties

Off-White Solid

The Uses of DULCIN

Dulcin is a non-nutritive sweetener. Dulcin is a sweet analgesic for use in medical procedures or treatments.

What are the applications of Application

Glycosine is a chemical also known as N-(4-Ethoxyphenyl)urea and 1-(4-ethoxyphenyl) urea

Definition

ChEBI: Dulcin is a member of ureas.

Production Methods

4-Ethoxyphenylurea, dulcin, is produced from the addition of potassium cyanate to p-phenetidine hydrochloride in aqueous solution at room temperature or from mixing urea and p-phenetidine hydrochloride to a mixture of hydrochloric acid and glacial acetic acid.

General Description

White crystals.

Air & Water Reactions

Partially decomposes on heating in water; hydrolyzes in 0.1 N acetic acid. Slightly water soluble .

Reactivity Profile

DULCIN is an example of an amide. Amides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Safety Profile

Human poison by ingestion. Moderately toxic experimentally by ingestion. Human systemic effects by ingestion: somnolence, hallucinations, distorted perceptions, and changes in motor activity. In adults 20 to 40 g produces dizziness, nausea, methemoglobinemia, cyanosis, and hypotension. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.