Domperidone

Toxicity

Side effects include galactorrhea, gynecomastia, or menstrual irregularities.

The Uses of Domperidone

Domperidone is a medication that enhances peristalsis or contractions of the stomach and intestines. Domperidone is also used to treat nausea and vomiting caused by other medicines used to treat Parkinson's disease.

Background

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

Indications

For management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.

What are the applications of Application

Domperidone is a peripheral D2DR inhibitor

Side Effects

Common side effects of Domperidone include: headache, dry mouth, diarrhoea or abdominal cramps. They are usually mild and go away on their own. Serious adverse reactions include: seizures or cramps, fast or irregular heartbeat, itching, lumpy rash (hives), or severe allergic reactions.

Pharmacokinetics

Domperidone is a specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

Metabolism