Docarpamine
- CAS NO.：74639-40-0
- Empirical Formula: C21H30N2O8S
- Molecular Weight: 470.54
- MDL number: MFCD00867115
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:41
What is Docarpamine?
Description
Docarpamine is a cardiostimulant with diuretic activity launched in Japan for the treatment of circulatory insufficiency. It is an orally effective peripheral dopamine prodrug that is well absorbed from the gastrointestinal tract and converted to dopamine in vivo, which exerts renal vasodilatory and natriuretic effects by activating renal dopamine (DA1) receptors, and a positive inotropic effect by activating cardiac β1-receptors. It has been reported to be effective in treating patients with acute heart failure, shock and acute renal failure.
Originator
Tanabe Seiyaku (Japan)
The Uses of Docarpamine
Docarpamine maybe a usefule alternative to intravenous dopamine after cardiac surgery.
Definition
ChEBI: Docarpamine is an organic molecular entity.
brand name
Tanadopa
Properties of Docarpamine
| Melting point: | 85-90°; mp 105-108° (Nishiyama, 1992) |
| Boiling point: | 731.0±60.0 °C(Predicted) |
| alpha | D20 -15.6° (c = 2 in methanol) |
| Density | 1.222±0.06 g/cm3(Predicted) |
| pka | 14.51±0.46(Predicted) |
Safety information for Docarpamine
Computed Descriptors for Docarpamine
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