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HomeProduct name listDMEOB

DMEOB

Synonym(s):3-Methoxybenzaldehyde [(3-methoxyphenyl)methylene]hydrazone

DMEOB Structural

What is DMEOB?

The Uses of DMEOB

DMEOB is a negative allosteric modulator at mGluR-5 (1). These mGlu receptors maintain a modulatory role and act as drug targets for various neurological disorders including depression, schizophrenia and Parkinson’s.

What are the applications of Application

DMEOB is a negative allosteric modulator at mGluR-5

Biological Activity

Negative allosteric modulator of the metabotropic glutamate receptor mGlu 5 ; displays reversible non-competitive inhibition of mGlu 5 -mediated responses (IC 50 = 3 μ M).

Biochem/physiol Actions

Negative allosteric modulator at the metabotropic glutamate receptor mGluR5.

Properties of DMEOB

Melting point: 77-78 °C(Solv: ethanol (64-17-5))
Boiling point: 405.1±45.0 °C(Predicted)
Density  1.05±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  H2O: insoluble
form  solid
pka 6.46±0.50(Predicted)
color  yellow

Safety information for DMEOB

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Environment
GHS09
GHS Hazard Statements H318:Serious eye damage/eye irritation
H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for DMEOB

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