DMEOB

Synonym(s):3-Methoxybenzaldehyde [(3-methoxyphenyl)methylene]hydrazone

CAS NO.：40252-74-2
Empirical Formula: C16H16N2O2
Molecular Weight: 268.31
MDL number: MFCD01001892
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-09 19:38:33

What is DMEOB?

The Uses of DMEOB

DMEOB is a negative allosteric modulator at mGluR-5 (1). These mGlu receptors maintain a modulatory role and act as drug targets for various neurological disorders including depression, schizophrenia and Parkinson’s.

What are the applications of Application

DMEOB is a negative allosteric modulator at mGluR-5

Biological Activity

Negative allosteric modulator of the metabotropic glutamate receptor mGlu 5 ; displays reversible non-competitive inhibition of mGlu 5 -mediated responses (IC 50 = 3 μ M).

Biochem/physiol Actions

Negative allosteric modulator at the metabotropic glutamate receptor mGluR5.

Properties of DMEOB

Melting point:	77-78 °C(Solv: ethanol (64-17-5))
Boiling point:	405.1±45.0 °C(Predicted)
Density	1.05±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	H₂O: insoluble
form	solid
pka	6.46±0.50(Predicted)
color	yellow

Safety information for DMEOB

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Environment GHS09
GHS Hazard Statements	H318:Serious eye damage/eye irritation H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.