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HomeProduct name listDL-Pyroglutamic acid

DL-Pyroglutamic acid

Synonym(s):DL-5-Oxo-2-pyrrolidinecarboxylic acid;DL-Pyroglutamic acid

  • CAS NO.:149-87-1
  • Empirical Formula: C5H7NO3
  • Molecular Weight: 129.11
  • MDL number: MFCD00064322
  • EINECS: 205-748-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-25 20:05:57
DL-Pyroglutamic acid Structural

What is DL-Pyroglutamic acid?

Chemical properties

DL-Pyroglutamic acid is white crystalline powder

The Uses of DL-Pyroglutamic acid

DL-Pyroglutamic acid is used in the preparation of AZT steroid conjugates as potent anti-HIV agents.

The Uses of DL-Pyroglutamic acid

DL-2-Pyrrolidone-5-carboxylic Acid is used in the preparation of AZT steroid conjugates as potent anti-HIV agents.

Definition

ChEBI: An oxoproline having the oxo group placed at the 5-position. It is an intermediate metabolite in the glutathione cycle.

Flammability and Explosibility

Non flammable

Properties of DL-Pyroglutamic acid

Melting point: 183-185 °C(lit.)
Boiling point: 239.15°C (rough estimate)
Density  1.3816 (rough estimate)
vapor pressure  0Pa at 25℃
refractive index  1.4220 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  52g/l
pka 3.48±0.20(Predicted)
form  Crystalline Powder
color  White
PH 1.7 (50g/l, H2O, 20℃)
Water Solubility  5.67 g/100 mL (20 ºC)
BRN  82131
CAS DataBase Reference 149-87-1(CAS DataBase Reference)
NIST Chemistry Reference DL-5-Oxoproline(149-87-1)

Safety information for DL-Pyroglutamic acid

Signal word Warning
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for DL-Pyroglutamic acid

InChIKey ODHCTXKNWHHXJC-UHFFFAOYSA-N

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