DL-Pyroglutamic acid

Synonym(s):DL-5-Oxo-2-pyrrolidinecarboxylic acid;DL-Pyroglutamic acid

DL-Pyroglutamic acid is white crystalline powder

DL-Pyroglutamic acid is used in the preparation of AZT steroid conjugates as potent anti-HIV agents.

DL-2-Pyrrolidone-5-carboxylic Acid is used in the preparation of AZT steroid conjugates as potent anti-HIV agents.

ChEBI: An oxoproline having the oxo group placed at the 5-position. It is an intermediate metabolite in the glutathione cycle.

Non flammable

Melting point:	183-185 °C(lit.)
Boiling point:	239.15°C (rough estimate)
Density	1.3816 (rough estimate)
vapor pressure	0Pa at 25℃
refractive index	1.4220 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	52g/l
pka	3.48±0.20(Predicted)
form	Crystalline Powder
color	White
PH	1.7 (50g/l, H2O, 20℃)
Water Solubility	5.67 g/100 mL (20 ºC)
BRN	82131
CAS DataBase Reference	149-87-1(CAS DataBase Reference)
NIST Chemistry Reference	DL-5-Oxoproline(149-87-1)

Signal word	Warning
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.