DL-KYNURENINE
Synonym(s):2-Amino-3-(2-aminobenzoyl)propionic acid;2-Amino-4-(2-aminophenyl)-4-oxobutyric acid
- CAS NO.：343-65-7
- Empirical Formula: C10H12N2O3
- Molecular Weight: 208.22
- MDL number: MFCD00025194
- EINECS: 206-445-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is DL-KYNURENINE?
The Uses of DL-KYNURENINE
A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan
The Uses of DL-KYNURENINE
vasodilator, immunomodulator
The Uses of DL-KYNURENINE
A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan.
Definition
ChEBI: A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Purification Methods
Crystallise it from H2O or aqueous AcOH. The picrate has m 188.5-189o(dec) after crystallisation from H2O. (±)-Kynurenine has m 218o. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p2726 1961, Beilstein 14 III 1657, 14 IV 2562.]
Properties of DL-KYNURENINE
| Melting point: | ~235 °C (dec.) |
| Boiling point: | 347.41°C (rough estimate) |
| Density | 1.343±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.4830 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly), Water (Slightly, Heated, Sonicated) |
| form | Solid |
| pka | 2.21±0.23(Predicted) |
| color | Pale Yellow to Light Yellow |
| Merck | 13,5343 |
| BRN | 2697333 |
| CAS DataBase Reference | 343-65-7(CAS DataBase Reference) |
Safety information for DL-KYNURENINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DL-KYNURENINE
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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