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HomeProduct name listDL-KYNURENINE

DL-KYNURENINE

Synonym(s):2-Amino-3-(2-aminobenzoyl)propionic acid;2-Amino-4-(2-aminophenyl)-4-oxobutyric acid

  • CAS NO.:343-65-7
  • Empirical Formula: C10H12N2O3
  • Molecular Weight: 208.22
  • MDL number: MFCD00025194
  • EINECS: 206-445-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-07 21:39:59
DL-KYNURENINE Structural

What is DL-KYNURENINE?

The Uses of DL-KYNURENINE

A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan

The Uses of DL-KYNURENINE

vasodilator, immunomodulator

The Uses of DL-KYNURENINE

A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan.

Definition

ChEBI: A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Purification Methods

Crystallise it from H2O or aqueous AcOH. The picrate has m 188.5-189o(dec) after crystallisation from H2O. (±)-Kynurenine has m 218o. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p2726 1961, Beilstein 14 III 1657, 14 IV 2562.]

Properties of DL-KYNURENINE

Melting point: ~235 °C (dec.)
Boiling point: 347.41°C (rough estimate)
Density  1.343±0.06 g/cm3 (20 ºC 760 Torr)
refractive index  1.4830 (estimate)
storage temp.  2-8°C
solubility  Aqueous Acid (Slightly), Water (Slightly, Heated, Sonicated)
form  Solid
pka 2.21±0.23(Predicted)
color  Pale Yellow to Light Yellow
Merck  13,5343
BRN  2697333
CAS DataBase Reference 343-65-7(CAS DataBase Reference)

Safety information for DL-KYNURENINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for DL-KYNURENINE

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