DL-CAPROYLCARNITINE CHLORIDE
Synonym(s):DL -Caproylcarnitine chloride
- CAS NO.:6920-35-0
- Empirical Formula: C13H26ClNO4
- Molecular Weight: 295.8
- MDL number: MFCD00151472
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-06 15:28:16
What is DL-CAPROYLCARNITINE CHLORIDE?
The Uses of DL-CAPROYLCARNITINE CHLORIDE
(±)-Hexanoylcarnitine Chloride acts as a potential absorption-enhancing agents when used in drugs that are poorly absorbed, particularly in the gastrointestinal track.
What are the applications of Application
(±)-Hexanoylcarnitine chloride is an acetylcarnitine chloride (sc-203495) homolog
Biological Activity
(±)-hexanoylcarnitine chloride is an agonist for cholinergic and a homolog of acetylcarnitine chloride (cat no. b6273).acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-hexanoylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3].
Properties of DL-CAPROYLCARNITINE CHLORIDE
Melting point: | 156-158°C |
storage temp. | −20°C |
solubility | Methanol (Slightly), Water (Slightly) |
form | Solid |
color | White to Off-White |
Water Solubility | Soluble to 100 mM in water |
Stability: | Hygroscopic |
Safety information for DL-CAPROYLCARNITINE CHLORIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for DL-CAPROYLCARNITINE CHLORIDE
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