DL-2-AMINOADIPIC ACID
Synonym(s):DL -α-Aminoadipic acid
- CAS NO.：542-32-5
- Empirical Formula: C6H11NO4
- Molecular Weight: 161.16
- MDL number: MFCD00063119
- EINECS: 208-809-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is DL-2-AMINOADIPIC ACID?
Chemical properties
Crystalline
The Uses of DL-2-AMINOADIPIC ACID
DL-2-Aminoadipic acid is a labeled amino acid which is used in chemical research and as pharmaceutical intermediate.
The Uses of DL-2-AMINOADIPIC ACID
An amino acid isolated from Cholera vibrio
What are the applications of Application
DL-2-Aminoadipic acid is a glutamine synthetase inhibitor
Definition
ChEBI: An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.
Biochem/physiol Actions
DL-2-Aminoadipic acid (AAA) is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity.
Purification Methods
Crystallise the acid from H2O. Alternatively purify it by precipitating the Cu salt and decomposing
Properties of DL-2-AMINOADIPIC ACID
| Melting point: | 196-198 °C(lit.) |
| Boiling point: | 287.44°C (rough estimate) |
| Density | 1.333 |
| refractive index | 1.4230 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly) |
| form | Powder or Crystalline Powder |
| pka | 2.14, 4.21, 9.77(at 25℃) |
| color | White to off-white |
| Water Solubility | Soluble in water (2.2 mg/ml at 20°C), 1 M HCl (50 mg/ml), ethanol (slightly), ether (slightly), and 80% formic acid (25 mg/ml). |
| Merck | 14,416 |
| BRN | 1773077 |
| CAS DataBase Reference | 542-32-5(CAS DataBase Reference) |
Safety information for DL-2-AMINOADIPIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for DL-2-AMINOADIPIC ACID
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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