DITHIO-BIS-MALEIMIDOETHANE
- CAS NO.：71865-37-7
- Empirical Formula: C12H12N2O4S2
- Molecular Weight: 312.36
- MDL number: MFCD01863385
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:38
What is DITHIO-BIS-MALEIMIDOETHANE?
Chemical properties
White Solid
The Uses of DITHIO-BIS-MALEIMIDOETHANE
A sulfhydryl reactive homobifunctional crosslinking reagent. Spacer Arm: 13.3 Angstroms
The Uses of DITHIO-BIS-MALEIMIDOETHANE
A sulfhydryl reactive homobifunctional crosslinking reagent.Spacer Arm: 13.3 Angstroms
What are the applications of Application
DTME is a homobifunctional , thiol-cleavable, sulfhydryl-reactive crosslinker, 13.3 angstrom spacer arm
General Description
DTME is a homobifunctional, maleimide crosslinker for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e., oligomerization) or protein interactions. DTME is similar in length to BMH but differs in containing a disulfide bond in its spacer arm, allowing crosslinks with DTME to be cleaved with reducing agent such as dithiothreitol (DTT).
Properties of DITHIO-BIS-MALEIMIDOETHANE
| Melting point: | 124°C |
| Boiling point: | 518.6±35.0 °C(Predicted) |
| Density | 1.511±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly) |
| pka | -2.05±0.20(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| Stability: | Temperature Sensitve, Moisture Sensitive |
Safety information for DITHIO-BIS-MALEIMIDOETHANE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DITHIO-BIS-MALEIMIDOETHANE
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