DIHYDROCYCLOSPORIN A

CAS NO.：59865-15-5
Empirical Formula: C62H113N11O12
Molecular Weight: 1204.63
MDL number: MFCD08458303
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-04 20:04:50

What is DIHYDROCYCLOSPORIN A?

Chemical properties

White Solid

The Uses of DIHYDROCYCLOSPORIN A

Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections.

The Uses of DIHYDROCYCLOSPORIN A

A Cyclosporin A (C988900) analog, an immunosuppressant.

The Uses of DIHYDROCYCLOSPORIN A

Dihydrocyclosporin A (DHCsA-d) is cyclosporine A (CsA) derivative. DHCsA-d significantly inhibited promastigotes and intracellular amastigotes, but it is highly cytotoxic.

What are the applications of Application

Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A

Side Effects

Dihydrocyclosporine A has no obvious nephrotoxic effect, but it exhibits hepatotoxic effects, often leading to hypertension.

Properties of DIHYDROCYCLOSPORIN A

Melting point:	120-125?C
Boiling point:	1285.3±65.0 °C(Predicted)
Density	1.012±0.06 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Solid
pka	13.33±0.70(Predicted)
color	White