Dihydrochelerythrine
- CAS NO.：6880-91-7
- Empirical Formula: C21H19NO4
- Molecular Weight: 349.38
- MDL number: MFCD02183360
- EINECS: 200-258-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Dihydrochelerythrine?
Description
Dihydrochelerythrine is a benzophenanthridine alkaloid that has been found in Bocconia arborea and has diverse biological activities. It is active against S. aureus, S. faecalis, and C. albicans (MIC = 1.87 μg/ml for all). Dihydrochelerythrine inhibits secretion of the hepatitis B virus (HBV) antigens HBsAg and HBeAg from HepG2 2.2.15 cells (IC50s = <0.05 μM for both). It is cytotoxic to HCT8, BGC-823, and A2780 cancer cells (IC50s = 1.4, 0.4, and 3.5 μM, respectively).
The Uses of Dihydrochelerythrine
Dihydrochelerythrine is synthesized as a potential G-quadrulpex DNA stabilizing agent. It is used in phamacokinetic study of chelerythrine metabolites in agro-products.
Definition
ChEBI: Dihydrochelerythrine is a benzophenanthridine alkaloid.
Properties of Dihydrochelerythrine
| Melting point: | 164-165 °C |
| Boiling point: | 565.9±50.0 °C(Predicted) |
| Density | 1.291±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO : 50 mg/mL (143.11 mM; Need ultrasonic and warming) |
| form | Powder |
| pka | 2.36±0.20(Predicted) |
| color | White to off-white |
Safety information for Dihydrochelerythrine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for Dihydrochelerythrine
New Products
1-Amino-1-cyclohexanecarboxylic acid Cycloleucine 6-Bromo-3-iodo-1-methyl-1H-indazole 3-(2,4-Dimethoxybenzyl)dihydropyrimidine-2,4(1H,3H)-dione 7-Bromo-1H-indazole ELECTROLYTIC IRON POWDER 2-Methyl-2-phenylpropyl acetate 1-Aminocyclobutanecarboxylic acid 1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole hydrochloride Decanonitrile tert-butyl 4-(1H-benzo[d]iMidazol-2-yl)piperidine-1-carboxylate 4-Ethylbenzylamine Methyl 5-bromo-2-chloro-3-nitrobenzoate N-(5-Amino-2-methylphenyl)acetamide 2-Chloro-3-nitropyridine 5-Bromo-2,3-dimethoxypyridine methyl 6-chloro-2-(chloromethyl)nicotinate 2-methoxy-4-methyl-5-nitro pyridine 2-iodo-5-bromo pyridine 2-amino-4-methyl-5-nitro pyridine 5-Fluoro-2-Oxindole methyl L-alaninate hydrochloride diethyl L-glutamate hydrochloride Ethyl tosylcarbamateRelated products of tetrahydrofuran
You may like
-
Ethoxymethylenemalononitrile 99% HPLCView Details
123-06-8 -
3-hydroxy-2-nitrobenzoic acid 602-00-6 98%View Details
602-00-6 -
Diethyl Disulfide 99% HPLCView Details
110-81-6 -
2-((4-Aminopentyl)(ethyl)amino)ethanol 69559-11-1 98%View Details
69559-11-1 -
6285-05-8. 1-(4-chlorophenyl) propan-1-one 98%View Details
6285-05-8. -
4-chloro-3,5-dinitropyridine 98%View Details
-
401-95-6 99% HPLCView Details
401-95-6 -
171663-13-1 tert-Butyl 3-bromobenzylcarbamate 98%View Details
171663-13-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.