Difluoxacin hydrochloride
Synonym(s):6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methylpiperazino)-4-oxo-3-quinolinecarboxylic acid hydrochloride
- CAS NO.:91296-86-5
- Empirical Formula: C21H20ClF2N3O3
- Molecular Weight: 435.85
- MDL number: MFCD03840489
- EINECS: 1806241-263-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-02-21 21:32:25

What is Difluoxacin hydrochloride?
Description
Difloxacin is a fluoroquinolone antibiotic. It is active against isolates of anaerobic bacteria, including B. fragilis, as well as Fusobacterium and Actinomyces species with MIC values ranging from ≤0.125 to 8 μg/ml. It eliminates E. coli and B. fragilis infection in a rat intra-abdominal abscess model when administered at a dose of 40 mg/kg three times per day.
Chemical properties
Off-White to Pale Yellow Solid
The Uses of Difluoxacin hydrochloride
A fluoroquinolone antibacterial structurally related to norfloxacin.
The Uses of Difluoxacin hydrochloride
antibacterial, DNA gyrase inhibitor
The Uses of Difluoxacin hydrochloride
A quinolone antibacterial compound. Structurally related to norfloxacin
What are the applications of Application
Difloxacin hydrochloride is an antimicrobial quinolone antibiotic
Properties of Difluoxacin hydrochloride
Melting point: | >245°C (dec.) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Soluble in aqueous buffer |
form | powder |
color | White to off-white |
CAS DataBase Reference | 91296-86-5(CAS DataBase Reference) |
Safety information for Difluoxacin hydrochloride
Signal word | Warning |
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Difluoxacin hydrochloride
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