DIETHYL TERT-BUTYLMALONATE

CAS NO.：759-24-0
Empirical Formula: C11H20O4
Molecular Weight: 216.27
MDL number: MFCD00009152
EINECS: 212-067-5
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is DIETHYL TERT-BUTYLMALONATE?

The Uses of DIETHYL TERT-BUTYLMALONATE

Diethyl tert-butylmalonate is used in the preparation of enantiomers of 4-tert-butyl-3-isopropyl-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane 1-sulfide.

Purification Methods

Dissolve it in Et2O, wash with aqueous NaHCO3, H2O, dry (MgSO4), filter, evaporate and distil the residue. Identify by hydrolysis to the acid and determine the neutralisation equivalent (theor: 80.0). The acid has m 155-157o effervescence [Hauser et al. J Am Chem Soc 64 2715 1942, Bush & Beauchamp J Am Chem Soc 75 2949 1953]. [Beilstein 2 IV 2027.]

Properties of DIETHYL TERT-BUTYLMALONATE

Boiling point:	102-104 °C/11 mmHg (lit.)
Density	1.014 g/mL at 25 °C (lit.)
refractive index	n20/D 1.425(lit.)
Flash point:	195 °F
pka	13.74±0.46(Predicted)
Water Solubility	Immiscible with water.
BRN	1781709

Safety information for DIETHYL TERT-BUTYLMALONATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H227:Flammable liquids
Precautionary Statement Codes	P403+P235:Store in a well-ventilated place. Keep cool.