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HomeProduct name listDIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE

DIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE

Synonym(s):N-Methoxy-N-methyl-2-(diethyl phosphono)acetamide;N-Methoxy-N-methyl-phosphonoacetamide diethyl ester;Diethyl N-methoxy-N-methylphosphonoacetamide;Diethylphosphonoacetic acid N-methyl-N-methoxyamide

DIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE Structural

What is DIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE?

The Uses of DIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE

Reactant for:

  • Preparation of ring-expanded bryostatin analogs as antitumor agents
  • Asymmertic synthesis of pinnatoxins A and G via diastereoselective Ireland-Claisen rearrangement, ring closing metathesis, and cyclization
  • Rh2(II)-catalyzed nitro-group migration reactions
  • Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition reactions
  • Stereoselective synthesis of (+)-polyrhacitide A via aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction as the key steps
  • Preparation of substituted furans via olefin cross-metathesis

Properties of DIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE

Boiling point: 90 °C17 mm Hg(lit.)
Density  1.163 g/mL at 25 °C(lit.)
refractive index  n20/D 1.455(lit.)
Flash point: >230 °F
form  clear liquid
color  Colorless to Almost colorless
BRN  1875865
CAS DataBase Reference 124931-12-0

Safety information for DIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for DIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE

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