DIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE

Synonym(s):N-Methoxy-N-methyl-2-(diethyl phosphono)acetamide;N-Methoxy-N-methyl-phosphonoacetamide diethyl ester;Diethyl N-methoxy-N-methylphosphonoacetamide;Diethylphosphonoacetic acid N-methyl-N-methoxyamide

Reactant for:

Preparation of ring-expanded bryostatin analogs as antitumor agents
Asymmertic synthesis of pinnatoxins A and G via diastereoselective Ireland-Claisen rearrangement, ring closing metathesis, and cyclization
Rh2(II)-catalyzed nitro-group migration reactions
Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition reactions
Stereoselective synthesis of (+)-polyrhacitide A via aldol reaction, Horner-Wardsworth-Emmons reaction, Evans acetal intramolecular oxa-Michael reaction and diastereoselective syn reduction reaction as the key steps
Preparation of substituted furans via olefin cross-metathesis

Boiling point:	90 °C17 mm Hg(lit.)
Density	1.163 g/mL at 25 °C(lit.)
refractive index	n20/D 1.455(lit.)
Flash point:	>230 °F
form	clear liquid
color	Colorless to Almost colorless
BRN	1875865
CAS DataBase Reference	124931-12-0

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.