DIBENZYL MALONATE

CAS NO.：15014-25-2
Empirical Formula: C17H16O4
Molecular Weight: 284.31
MDL number: MFCD00004779
EINECS: 239-099-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is DIBENZYL MALONATE?

Chemical properties

CLEAR YELLOWISH LIQUID

The Uses of DIBENZYL MALONATE

Dibenzyl malonate was used in the preparation of tetraethyl 3,3-bis(benzyloxycarbonyl)propylene bisphosphonate. It was also used in the preparation of benzyl umbelliferone-3-carboxylate via Knoevenagel condensation with 2,4-dihydroxybezaldehyde.

General Description

Direct asymmetric reaction of dibenzyl malonate with N-tert-butoxycarbonyl aldimines in the presence of Yb(OTf)₃ and iPr-pybox (pybox = pyridine bisoxazoline) complexes has been investigated.

Purification Methods

Dissolve the ester in toluene, wash it with aqueous NaHCO3, H2O, dry over MgSO4, filter, evaporate and distil it at high vacuum. [Ginsburg & Pappo J Am Chem Soc 75 1094 1953, Baker et al. J Org Chem 17 77 1952, Beilstein 6 IV 2270.]

Properties of DIBENZYL MALONATE

Boiling point:	188 °C/0.2 mmHg (lit.)
Density	1.137 g/mL at 25 °C (lit.)
refractive index	n20/D 1.546(lit.)
Flash point:	>230 °F
storage temp.	Sealed in dry,Room Temperature
form	clear liquid
pka	11.65±0.46(Predicted)
Specific Gravity	1.17
color	Colorless to Light yellow to Light orange
Water Solubility	Sparingly soluble in water; miscible in all proportions with ether and alcohol.
BRN	1998264
CAS DataBase Reference	15014-25-2(CAS DataBase Reference)

Safety information for DIBENZYL MALONATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.