DIBENZYL DIETHYLPHOSPHORAMIDITE
Synonym(s):TTC
- CAS NO.：67746-43-4
- Empirical Formula: C18H24NO2P
- Molecular Weight: 317.36
- MDL number: MFCD00191987
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:44:00
What is DIBENZYL DIETHYLPHOSPHORAMIDITE?
Chemical properties
Clear Colourless Liquid
The Uses of DIBENZYL DIETHYLPHOSPHORAMIDITE
Dibenzyl diethylphosphoramidite is a useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters as well as dibenzyl glycosyl phosphites, which can easily be converted to glycosyl phosphates or used in glycosylation reagents in oligosaccharide synthesis.
The Uses of DIBENZYL DIETHYLPHOSPHORAMIDITE
Dibenzyl N,N-diethylphosphoramidite may be used:
- as phosphitylating reagent in the synthesis of glycosyl phosphites and phosphates
- for phosphorylating the alcohols
- in the preparation of 6-dibenzylphosphate-1,3,5-tri-O-PMB-myo-inositol
General Description
Dibenzyl N,N-diethylphosphoramidite is repoted to be suitable reagent for the efficient 1H-tetrazole-catalyzed ′phosphite-triester′ phosphorylation of the protected serine derivatives.
Properties of DIBENZYL DIETHYLPHOSPHORAMIDITE
| Boiling point: | 131-132 °C(Press: 0.0001 Torr) |
| Density | 1.06 g/mL at 25 °C(lit.) |
| vapor pressure | 0.71 psi ( 55 °C) |
| refractive index | n |
| Flash point: | 95 °F |
| storage temp. | 2-8°C |
| solubility | Soluble in chloroform. |
| pka | 4.01±0.70(Predicted) |
| form | Oil |
| color | Clear Colourless to Pale Yellow |
| Sensitive | Moisture Sensitive |
| BRN | 4189915 |
| Stability: | Light Sensitive |
| CAS DataBase Reference | 67746-43-4 |
Safety information for DIBENZYL DIETHYLPHOSPHORAMIDITE
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for DIBENZYL DIETHYLPHOSPHORAMIDITE
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![BIS[1-(2-NITROPHENYL)ETHYL] N,N-DIISOPROPYLPHOSPHORAMIDITE](https://img.chemicalbook.in/StructureFile/ChemBookStructure22/GIF/CB2648389.gif)
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