DIBENZYL DIETHYLPHOSPHORAMIDITE

Synonym(s):TTC

CAS NO.：67746-43-4
Empirical Formula: C18H24NO2P
Molecular Weight: 317.36
MDL number: MFCD00191987
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-15 10:44:00

DIBENZYL DIETHYLPHOSPHORAMIDITE Structural

What is DIBENZYL DIETHYLPHOSPHORAMIDITE?

Chemical properties

Clear Colourless Liquid

The Uses of DIBENZYL DIETHYLPHOSPHORAMIDITE

Dibenzyl diethylphosphoramidite is a useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters as well as dibenzyl glycosyl phosphites, which can easily be converted to glycosyl phosphates or used in glycosylation reagents in oligosaccharide synthesis.

The Uses of DIBENZYL DIETHYLPHOSPHORAMIDITE

Dibenzyl N,N-diethylphosphoramidite may be used:

as phosphitylating reagent in the synthesis of glycosyl phosphites and phosphates
for phosphorylating the alcohols
in the preparation of 6-dibenzylphosphate-1,3,5-tri-O-PMB-myo-inositol

General Description

Dibenzyl N,N-diethylphosphoramidite is repoted to be suitable reagent for the efficient 1H-tetrazole-catalyzed ′phosphite-triester′ phosphorylation of the protected serine derivatives.

Properties of DIBENZYL DIETHYLPHOSPHORAMIDITE

Boiling point:	131-132 °C(Press: 0.0001 Torr)
Density	1.06 g/mL at 25 °C(lit.)
vapor pressure	0.71 psi ( 55 °C)
refractive index	n20/D 1.545(lit.)
Flash point:	95 °F
storage temp.	2-8°C
solubility	Soluble in chloroform.
pka	4.01±0.70(Predicted)
form	Oil
color	Clear Colourless to Pale Yellow
Sensitive	Moisture Sensitive
BRN	4189915
Stability:	Light Sensitive
CAS DataBase Reference	67746-43-4

Safety information for DIBENZYL DIETHYLPHOSPHORAMIDITE

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.