DEVAZEPIDE
Synonym(s):(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide;L-364,718;MK 329
- CAS NO.：103420-77-5
- Empirical Formula: C25H20N4O2
- Molecular Weight: 408.45
- MDL number: MFCD00864500
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is DEVAZEPIDE?
The Uses of DEVAZEPIDE
Devazepide has been used as a cholecystokinin receptor 1 (CCK1R) antagonist in human embryonic kidney 293T cells and in human pancreatic slices.
The Uses of DEVAZEPIDE
Antagonist (cholecystokinin).
What are the applications of Application
Devazepide is a potent CCK (cholecystokinin) inhibitor
Definition
ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f r treatment of gastrointestinal disorders.
General Description
Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone.
Biochem/physiol Actions
Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist.
storage
Store at +4°C
Properties of DEVAZEPIDE
| Boiling point: | 758.6±60.0 °C(Predicted) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: >5mg/mL |
| pka | 13.25±0.40(Predicted) |
| form | powder |
| color | white to off-white |
Safety information for DEVAZEPIDE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H300:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for DEVAZEPIDE
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![3-AMINO-5-METHYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE](https://img.chemicalbook.in/CAS/GIF/205989-36-2.gif)
![N-(2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-ACETAMIDE](https://img.chemicalbook.in/CAS/GIF/70890-53-8.gif)
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