DEVAZEPIDE

Synonym(s):(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide;L-364,718;MK 329

CAS NO.：103420-77-5
Empirical Formula: C25H20N4O2
Molecular Weight: 408.45
MDL number: MFCD00864500
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 23:16:16

What is DEVAZEPIDE?

The Uses of DEVAZEPIDE

Devazepide has been used as a cholecystokinin receptor 1 (CCK1R) antagonist in human embryonic kidney 293T cells and in human pancreatic slices.

The Uses of DEVAZEPIDE

Antagonist (cholecystokinin).

What are the applications of Application

Devazepide is a potent CCK (cholecystokinin) inhibitor

Definition

ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f r treatment of gastrointestinal disorders.

General Description

Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone.

Biochem/physiol Actions

Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist.

storage

Store at +4°C

Properties of DEVAZEPIDE

Boiling point:	758.6±60.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: >5mg/mL
pka	13.25±0.40(Predicted)
form	powder
color	white to off-white

Safety information for DEVAZEPIDE

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H300:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.