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HomeProduct name listDesthiobiotin-PEG4-Alkyne

Desthiobiotin-PEG4-Alkyne

  • CAS NO.:1802907-99-8
  • Empirical Formula: C21H37N3O6
  • Molecular Weight: 427.54
  • MDL number: MFCD28505545
  • Update Date: 2024-03-21 17:31:59
Desthiobiotin-PEG4-Alkyne Structural

What is Desthiobiotin-PEG4-Alkyne?

Description

Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin.

Properties of Desthiobiotin-PEG4-Alkyne

Boiling point: 649.0±50.0 °C(Predicted)
Density  1.075±0.06 g/cm3(Predicted)
pka 14.93±0.60(Predicted)

Safety information for Desthiobiotin-PEG4-Alkyne

Computed Descriptors for Desthiobiotin-PEG4-Alkyne

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