Dde Biotin-PEG4-Azide
- CAS NO.:1802907-93-2
- Empirical Formula: C32H53N7O8S
- Molecular Weight: 695.88
- MDL number: MFCD28505550
- Update Date: 2024-03-21 13:23:50
What is Dde Biotin-PEG4-Azide?
Description
Dde Biotin-PEG4-azide is useful for introducing a biotin moiety to alkyne-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Dde protecting group allows efficient release of captured biotinylated molecules from streptavidin under mild conditions with hydrazine.
The Uses of Dde Biotin-PEG4-Azide
Extraordinary strength of the streptavidin-biotin interaction allows for efficient capturing of even highly dilute targets; however, it makes recovery of proteins from affinity resins challenging. This reagent contains a biotin moiety linked to an azide moiety through a spacer arm containing a hydrazine-cleavable Dde linker. Typically >90% of captured biomolecules can be efficiently released.
Properties of Dde Biotin-PEG4-Azide
storage temp. | 2-8°C |
Safety information for Dde Biotin-PEG4-Azide
Computed Descriptors for Dde Biotin-PEG4-Azide
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